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  4. Recombinant Human Transmembrane protease serine 9 (TMPRSS9), partial

Recombinant Human Transmembrane protease serine 9 (TMPRSS9), partial

  • 中文名称：
    人TMPRSS9重组蛋白
  • 货号：
    CSB-YP772017HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TMPRSS9重组蛋白
  • 货号：
    CSB-EP772017HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TMPRSS9重组蛋白
  • 货号：
    CSB-EP772017HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TMPRSS9重组蛋白
  • 货号：
    CSB-BP772017HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TMPRSS9重组蛋白
  • 货号：
    CSB-MP772017HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TMPRSS9
  • Uniprot No.：
    Q7Z410
  • 别名：
    TMPRSS9; Transmembrane protease serine 9; EC 3.4.21.-; Polyserase-I; Polyserine protease 1; Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3]
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Serase-1 and serase-2 are serine proteases that hydrolyze the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC. In contrast, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Ala-Pro-Ala-AMC are not significantly hydrolyzed.
  • 基因功能参考文献：
    1. These effects were mediated by the efficient conversion of pro-uPA to active uPA and high phosphorylation levels of ERK detected in the PANC-1 cells expressing exogenous polyserase-1. PMID: 24756697
    2. SNP rs4806846 in TMPRSS9 gene is associated with neuroticism in a European sample. PMID: 23229837
    3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    4. Polyserase-I is a human polyprotease with the ability to generate independent serine protease domains from a single translation product PMID: 12886014
    5. The isolation and characterization of serase-1B, a splice variant of polyserase-1, is reported (accession AB109390.1). PMID: 16872279

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  • 亚细胞定位：
    Cell membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Peptidase S1 family
  • 组织特异性：
    Expressed in fetal human tissues, such as kidney, liver, lung and brain, and in a variety of tumor cell lines. Weakly expressed in adult tissues including skeletal muscle, liver, placenta and heart.
  • 数据库链接：

    HGNC: 30079

    OMIM: 610477

    KEGG: hsa:360200

    STRING: 9606.ENSP00000330264

    UniGene: Hs.465560

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