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Recombinant Human Translation initiation factor IF-2, mitochondrial (MTIF2)

  • 中文名称:
    人MTIF2重组蛋白
  • 货号:
    CSB-YP015164HU
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 中文名称:
    人MTIF2重组蛋白
  • 货号:
    CSB-EP015164HU
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 中文名称:
    人MTIF2重组蛋白
  • 货号:
    CSB-EP015164HU-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名称:
    人MTIF2重组蛋白
  • 货号:
    CSB-BP015164HU
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 中文名称:
    人MTIF2重组蛋白
  • 货号:
    CSB-MP015164HU
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    MTIF2
  • Uniprot No.:
  • 别名:
    IF-2(Mt); IF-2Mt; IF2(mt); IF2M_HUMAN; mitochondrial; mitochondrial translational initiation factor 2; Mtif2; Translation initiation factor IF-2; Translation initiation factor IF-2; mitochondrial
  • 种属:
    Homo sapiens (Human)
  • 蛋白长度:
    Full Length of Mature Protein
  • 表达区域:
    30-727
  • 氨基酸序列
    L RQWRHGFSSA YPVWTAQLCA WPWPTDVLTG AALSQYRLLV TKKEEGPWKS QLSSTKSKKV VEVWIGMTIE ELARAMEKNT DYVYEALLNT DIDIDSLEAD SHLDEVWIKE VITKAGMKLK WSKLKQDKVR KNKDAVRRPQ ADPALLTPRS PVVTIMGHVD HGKTTLLDKF RKTQVAAVET GGITQHIGAF LVSLPSGEKI TFLDTPGHAA FSAMRARGAQ VTDIVVLVVA ADDGVMKQTV ESIQHAKDAQ VPIILAVNKC DKAEADPEKV KKELLAYDVV CEDYGGDVQA VPVSALTGDN LMALAEATVA LAEMLELKAD PNGPVEGTVI ESFTDKGRGL VTTAIIQRGT LRKGSVLVAG KCWAKVRLMF DENGKTIDEA YPSMPVGITG WRDLPSAGEE ILEVESEPRA REVVDWRKYE QEQEKGQEDL KIIEEKRKEH KEAHQKAREK YGHLLWKKRS ILRFLERKEQ IPLKPKEKRE RDSNVLSVII KGDVDGSVEA ILNIIDTYDA SHECELELVH FGVGDVSAND VNLAETFDGV IYGFNVNAGN VIQQSAAKKG VKIKLHKIIY RLVEDLQEEL SSRLPCAVEE HPVGEASILA TFSVTEGKKK VPVAGCRVQK GQLEKQKKFK LTRNGHVIWK GSLTSLKHHK DDISIVKTGM DCGLSLDEDN MEFQVGDRIV CYEEKQIQAK TSWDPGF
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
  • 基因功能参考文献:
    1. This study identified a novel GWS association (1.17 x 10(-10)) mapped to chromosome 2 at rs1437396, between MTIF2 and CCDC88A, across all of the EA and AA cohorts. PMID: 24166409
  • 亚细胞定位:
    Mitochondrion.
  • 蛋白家族:
    TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, IF-2 subfamily
  • 组织特异性:
    Expressed in all tissues examined. Highest level in skeletal muscle.
  • 数据库链接:

    HGNC: 7441

    OMIM: 603766

    KEGG: hsa:4528

    STRING: 9606.ENSP00000263629

    UniGene: Hs.149894