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  4. Recombinant Human Transcription factor TFIIIB component B' homolog (BDP1), partial

Recombinant Human Transcription factor TFIIIB component B' homolog (BDP1), partial

  • 中文名称：
    Recombinant Human Transcription factor TFIIIB component B' homolog(BDP1) ,partial
  • 货号：
    CSB-YP406639HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Transcription factor TFIIIB component B' homolog(BDP1) ,partial
  • 货号：
    CSB-EP406639HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Transcription factor TFIIIB component B' homolog(BDP1) ,partial
  • 货号：
    CSB-EP406639HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Transcription factor TFIIIB component B' homolog(BDP1) ,partial
  • 货号：
    CSB-BP406639HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Transcription factor TFIIIB component B' homolog(BDP1) ,partial
  • 货号：
    CSB-MP406639HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    BDP1
  • Uniprot No.：
    A6H8Y1
  • 别名：
    BDP1; KIAA1241; KIAA1689; TFNRTranscription factor TFIIIB component B'' homolog; Transcription factor IIIB 150; TFIIIB150; Transcription factor-like nuclear regulator
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    General activator of RNA polymerase III transcription. Requires for transcription from all three types of polymerase III promoters. Requires for transcription of genes with internal promoter elements and with promoter elements upstream of the initiation site.
  • 基因功能参考文献：
    1. Linkage study and exome sequencing identify a BDP1 mutation associated with hereditary hearing loss. PMID: 24312468
    2. Human BDP1 protein represents essential components of TFIIIC1 and TFIIIC1-like activities. PMID: 15096501
    3. Maf1 occupancy of Pol III genes is inversely correlated with that of the initiation factor TFIIIB (subunit Bdp1) and Pol III PMID: 17499043
    4. PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex PMID: 18391023
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Isoform 2 is highly expressed in cerebellum.
  • 数据库链接：

    HGNC: 13652

    OMIM: 607012

    KEGG: hsa:55814

    STRING: 9606.ENSP00000351575

    UniGene: Hs.258272

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