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  4. Recombinant Human Synaptonemal complex protein 1 (SYCP1), partial

Recombinant Human Synaptonemal complex protein 1 (SYCP1), partial

  • 中文名称：
    人SYCP1重组蛋白
  • 货号：
    CSB-YP022990HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SYCP1重组蛋白
  • 货号：
    CSB-EP022990HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SYCP1重组蛋白
  • 货号：
    CSB-EP022990HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SYCP1重组蛋白
  • 货号：
    CSB-BP022990HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SYCP1重组蛋白
  • 货号：
    CSB-MP022990HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SYCP1
  • Uniprot No.：
    Q15431
  • 别名：
    Cancer/testis antigen 8; CT8; HOM TES 14; MGC104417; SCP 1; SCP-1; SCP1; SYCP 1; Sycp1; SYCP1_HUMAN; Synaptonemal complex protein 1; Testicular tissue protein Li 191
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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SYCP1 antibodies

靶点详情

  • 功能：
    Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.
  • 基因功能参考文献：
    1. Crystal structure of C-terminal coiled-coil domain of SYCP1 reveals non-canonical anti-parallel dimeric structure of transverse filament at the synaptonemal complex. PMID: 27548613
    2. crystal structure of the middle part of the human synaptonemal complex protein 1 coiled-coil domain PMID: 26323297
    3. SYCP1, cTAGE1, and GTSF1 are expressed in cutaneous T-cell lymphoma, but not in normal skin or benign inflammatory dermatoses. PMID: 24850846
    4. Cancer-Testis Antigen SCP-1 mRNA is expressed in some nasopharyngeal carcinoma. PMID: 17608150
    5. an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4+ T cells PMID: 16030183

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  • 亚细胞定位：
    Nucleus. Chromosome. Chromosome, centromere.
  • 组织特异性：
    Testis.
  • 数据库链接：

    HGNC: 11487

    OMIM: 602162

    KEGG: hsa:6847

    STRING: 9606.ENSP00000358531

    UniGene: Hs.112743

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