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  4. Recombinant Human Splicing factor, arginine/serine-rich 19 (SCAF1), partial

Recombinant Human Splicing factor, arginine/serine-rich 19 (SCAF1), partial

  • 中文名称：
    人SCAF1重组蛋白
  • 货号：
    CSB-YP887996HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SCAF1重组蛋白
  • 货号：
    CSB-EP887996HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SCAF1重组蛋白
  • 货号：
    CSB-EP887996HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SCAF1重组蛋白
  • 货号：
    CSB-BP887996HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SCAF1重组蛋白
  • 货号：
    CSB-MP887996HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SCAF1
  • Uniprot No.：
    Q9H7N4
  • 别名：
    SCAF1; SFRS19; SRA1; Splicing factor; arginine/serine-rich 19; SR-related C-terminal domain-associated factor 1; SR-related and CTD-associated factor 1; SR-related-CTD-associated factor; SCAF; Serine arginine-rich pre-mRNA splicing factor SR-A1; SR-A1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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SCAF1 antibodies

靶点详情

  • 功能：
    May function in pre-mRNA splicing.
  • 基因功能参考文献：
    1. This is the first study that examines the expression of the novel gene SR-A1 in colon cancer progression. PMID: 15493872
    2. Study describes the discovery and cloning of fifteen novel splice variants of SCAF1 gene in cancer cells comprising a total of nine novel alternative splicing events between the annotated exons of the gene, producing seven novel SCAF1 transcripts with open-reading frames, and eight novel SCAF1 transcripts with premature termination codons that are likely long non-coding RNAs. Additionally, a novel 3' UTR was discovered. PMID: 29787824
    3. This study unveils the presence of SR-A1, CD36, and LOX-1 in aortic valves and suggests potential mechanisms by which they may contribute to the pathological angiogenesis, inflammation, calcification, and lipid accumulation in AVS. PMID: 24929820
    4. Our results suggest that SRA1 is associated with cancer progression and may possibly be characterized as a new marker of unfavorable prognosis for ovarian cancer. PMID: 16631123
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Splicing factor SR family
  • 组织特异性：
    Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.
  • 数据库链接：

    HGNC: 30403

    OMIM: 617264

    KEGG: hsa:58506

    STRING: 9606.ENSP00000353769

    UniGene: Hs.103521

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