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Recombinant Human Spectrin beta chain, brain 4 (SPTBN5), partial

  • 中文名称:
    人SPTBN5重组蛋白
  • 货号:
    CSB-YP878864HU
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 中文名称:
    人SPTBN5重组蛋白
  • 货号:
    CSB-EP878864HU
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 中文名称:
    人SPTBN5重组蛋白
  • 货号:
    CSB-EP878864HU-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名称:
    人SPTBN5重组蛋白
  • 货号:
    CSB-BP878864HU
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 中文名称:
    人SPTBN5重组蛋白
  • 货号:
    CSB-MP878864HU
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    SPTBN5
  • Uniprot No.:
  • 别名:
    Beta-V spectrin; brain 4; BSPECV; HUBSPECV; HUSPECV; non-erythroid beta chain 4; Spectrin; Spectrin beta chain; Spectrin beta chain, brain 4; Spectrin, non-erythroid beta chain 4; SPTBN4; SPTBN5; SPTN5_HUMAN
  • 种属:
    Homo sapiens (Human)
  • 蛋白长度:
    Partial
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献:
    1. Adaptive mutations of spectrin-betaV occurred in the mammalian lineage and were accompanied with substantial changes in the protein distribution within inner ear hair cells. PMID: 28179572
    2. study identified spectrin betaV as a myosin VIIa- and rhodopsin-interacting partner in photoreceptor cells; suggest that spectrin betaV homomers couple some USH1 proteins, opsin and other phototransduction proteins to both actin- and microtubule-based motors, thereby contributing to their transport towards the photoreceptor outer disks PMID: 23704327
    3. interaction of hTRPC4 with alphaII-spectrin and betaV-spectrin was confirmed by glutathione S-transferase pulldown and co-immunoprecipitation experiments PMID: 18048348
  • 亚细胞定位:
    Cytoplasm, cytoskeleton. Note=Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.
  • 蛋白家族:
    Spectrin family
  • 组织特异性:
    Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.
  • 数据库链接:

    HGNC: 15680

    OMIM: 605916

    KEGG: hsa:51332

    STRING: 9606.ENSP00000317790

    UniGene: Hs.709819