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  4. Recombinant Human Sal-like protein 3 (SALL3), partial

Recombinant Human Sal-like protein 3 (SALL3), partial

  • 中文名称：
    人SALL3重组蛋白
  • 货号：
    CSB-YP866302HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SALL3重组蛋白
  • 货号：
    CSB-EP866302HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SALL3重组蛋白
  • 货号：
    CSB-EP866302HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SALL3重组蛋白
  • 货号：
    CSB-BP866302HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SALL3重组蛋白
  • 货号：
    CSB-MP866302HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SALL3
  • Uniprot No.：
    Q9BXA9
  • 别名：
    SALL3; ZNF796; Sal-like protein 3; Zinc finger protein 796; Zinc finger protein SALL3; hSALL3
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable transcription factor.
  • 基因功能参考文献：
    1. Results found that SALL3 promoter methylation was associated with its transcriptional inhibition. Also, hypermethylation of CpG islands in the SALL3 promoter was independently associated with aggressive behavior of head and neck cancer (HNSCC) tumors, suggesting that SALL3 acts as a tumor suppressor gene and can serve as a prognostic biomarker in HNSCC. PMID: 28616099
    2. sall3 shows aberrant methylation and downregulation in human hepatocellular carcinoma PMID: 22690083
    3. Studies indicate that vertebrate sal orthologues (spalt-like/sall) have important developmental roles during neural development and organogenesis and gentic diseases. PMID: 19247946
    4. This functional characterization of SALL3 sheds light on regulatory mechanisms for DNMT3A and provides new strategies to inhibit aberrant methylation in cancer. PMID: 19139273
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Sal C2H2-type zinc-finger protein family
  • 组织特异性：
    Widely expressed in adult with highest levels in heart. Expressed in fetal brain (in neurons of hippocampus, cortex, mediodorsal and ventrolateral thalamic nuclei, putamen, cerebellum and brainstem).
  • 数据库链接：

    HGNC: 10527

    OMIM: 605079

    KEGG: hsa:27164

    STRING: 9606.ENSP00000441823

    UniGene: Hs.700557

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