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Recombinant Human SEC23-interacting protein (SEC23IP), partial

  • 中文名称:
    人SEC23IP重组蛋白
  • 货号:
    CSB-YP896767HU
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 中文名称:
    人SEC23IP重组蛋白
  • 货号:
    CSB-EP896767HU
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 中文名称:
    人SEC23IP重组蛋白
  • 货号:
    CSB-EP896767HU-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名称:
    人SEC23IP重组蛋白
  • 货号:
    CSB-BP896767HU
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 中文名称:
    人SEC23IP重组蛋白
  • 货号:
    CSB-MP896767HU
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    SEC23IP
  • Uniprot No.:
  • 别名:
    MSTP053; p125; P125A; Phospholipase; S23IP_HUMAN; Sec23 interacting protein p125; SEC23-interacting protein; SEC23IP
  • 种属:
    Homo sapiens (Human)
  • 蛋白长度:
    Partial
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
  • 基因功能参考文献:
    1. A basic cluster and a hydrophobic interface in the DDHD and SAM domains, respectively, are required for p125A-mediated functional endoplasmic reticulum exit site assembly. PMID: 24522181
    2. Xenopus sec23ip is required for normal neural crest cell development, suggesting a role for the human ortholog in Waardenburg syndrome neural crest defects. PMID: 20308572
    3. The results suggest that p125A is part of the Sec13/Sec31A subcomplex and facilitates ER export in mammalian cells. PMID: 20679433
    4. p125 is a mammalian-specific component of ER exit sites and participates in the organization of this compartment PMID: 15623529
  • 亚细胞定位:
    Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum.
  • 蛋白家族:
    PA-PLA1 family
  • 组织特异性:
    Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.
  • 数据库链接:

    HGNC: 17018

    OMIM: 617852

    KEGG: hsa:11196

    STRING: 9606.ENSP00000358071

    UniGene: Hs.435004