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  4. Recombinant Human SCY1-like protein 2 (SCYL2), partial

Recombinant Human SCY1-like protein 2 (SCYL2), partial

  • 中文名称：
    人SCYL2重组蛋白
  • 货号：
    CSB-YP747403HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SCYL2重组蛋白
  • 货号：
    CSB-EP747403HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SCYL2重组蛋白
  • 货号：
    CSB-EP747403HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SCYL2重组蛋白
  • 货号：
    CSB-BP747403HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SCYL2重组蛋白
  • 货号：
    CSB-MP747403HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SCYL2
  • Uniprot No.：
    Q6P3W7
  • 别名：
    AU015688; AW536445; BC030932; Coated vesicle-associated kinase of 104 kDa; CVAK104; D10Ertd802e; FLJ10074; KIAA1360; RGD1305665; SCY1 like 2 (S. cerevisiae); SCY1 like protein 2; SCY1-like protein 2; SCYL2; SCYL2_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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SCYL2 antibodies

靶点详情

  • 功能：
    Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system. A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed. By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development.
  • 基因功能参考文献：
    1. results suggest that SCYL2 serves as a regulatory factor for Vpu, reducing the extent of Vpu phosphorylation and consequently enhancing BST2-mediated viral restriction. PMID: 23047923
    2. CVAK104 binds ATP and functions in vitro as a poly-L-lysine-stimulated kinase that is capable of autophosphorylation and phosphorylating the beta2-adaptin subunit of AP2. PMID: 15809293
    3. Together, our data suggest a function for CVAK104 in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. PMID: 16914521
    4. CVAK104 is an evolutionarily conserved protein involved in SNARE sorting that is essential for normal embryonic development PMID: 17587408
    5. Studies identify CVAK104 as a novel binding partner of Dishevelled (Dvl) and that CVAK104 also interacts with Fzd5. PMID: 19643732

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  • 亚细胞定位：
    Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network membrane. Endosome membrane.
  • 蛋白家族：
    Protein kinase superfamily
  • 数据库链接：

    HGNC: 19286

    OMIM: 616365

    KEGG: hsa:55681

    STRING: 9606.ENSP00000354061

    UniGene: Hs.506481

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