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  4. Recombinant Human Rho guanine nucleotide exchange factor 17 (ARHGEF17), partial

Recombinant Human Rho guanine nucleotide exchange factor 17 (ARHGEF17), partial

  • 中文名称：
    Recombinant Human Rho guanine nucleotide exchange factor 17(ARHGEF17) ,partial
  • 货号：
    CSB-YP839390HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Rho guanine nucleotide exchange factor 17(ARHGEF17) ,partial
  • 货号：
    CSB-EP839390HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Rho guanine nucleotide exchange factor 17(ARHGEF17) ,partial
  • 货号：
    CSB-EP839390HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Rho guanine nucleotide exchange factor 17(ARHGEF17) ,partial
  • 货号：
    CSB-BP839390HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Rho guanine nucleotide exchange factor 17(ARHGEF17) ,partial
  • 货号：
    CSB-MP839390HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ARHGEF17
  • Uniprot No.：
    Q96PE2
  • 别名：
    ARHGEF17; KIAA0337; TEM4Rho guanine nucleotide exchange factor 17; 164 kDa Rho-specific guanine-nucleotide exchange factor; p164-RhoGEF; p164RhoGEF; Tumor endothelial marker 4
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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ARHGEF17 antibodies

靶点详情

  • 功能：
    Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.
  • 基因功能参考文献：
    1. data implicate TEM4 as an essential regulator of the actin cytoskeleton that ensures proper membrane protrusion at the leading edge of migrating cells and efficient cellular migration via suppression of actomyosin contractility PMID: 23825001
    2. Interaction of the central domain of ARHGEF17 with Mps1. PMID: 26953350
    3. The rho guanine nucleotide exchange factor 17 is drastically alter the effect of cGMP/cGK involving signaling pathways on RhoA-activated downstream effectors. PMID: 23195829
    4. TEM4 contains a novel actin binding domain and binding to actin is essential for TEM4 subcellular localization and activity. PMID: 22911862
    5. a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart PMID: 12071859
    6. Identification of ARHGEF17, mutations in melanoma. PMID: 18677770

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  • 组织特异性：
    Highly expressed in the heart.
  • 数据库链接：

    HGNC: 21726

    KEGG: hsa:9828

    STRING: 9606.ENSP00000263674

    UniGene: Hs.533719

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