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  4. Recombinant Human Rho GTPase-activating protein 20 (ARHGAP20), partial

Recombinant Human Rho GTPase-activating protein 20 (ARHGAP20), partial

  • 中文名称：
    Recombinant Human Rho GTPase-activating protein 20(ARHGAP20) ,partial
  • 货号：
    CSB-YP885801HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Rho GTPase-activating protein 20(ARHGAP20) ,partial
  • 货号：
    CSB-EP885801HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Rho GTPase-activating protein 20(ARHGAP20) ,partial
  • 货号：
    CSB-EP885801HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Rho GTPase-activating protein 20(ARHGAP20) ,partial
  • 货号：
    CSB-BP885801HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Rho GTPase-activating protein 20(ARHGAP20) ,partial
  • 货号：
    CSB-MP885801HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ARHGAP20
  • Uniprot No.：
    Q9P2F6
  • 别名：
    ARHGAP20; KIAA1391; Rho GTPase-activating protein 20; Rho-type GTPase-activating protein 20
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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ARHGAP20 antibodies

靶点详情

  • 功能：
    GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
  • 基因功能参考文献：
    1. The similar expression profiles of ARHGAP20 in 13q14 and 11q22-23 deleted CLL cases suggest a molecular connection and an intriguing mechanism of regulation PMID: 21500311
    2. human KIAA1391 gene and mouse Kiaa1391 gene encode RhoGAP proteins with RA domain and two ANXL repeats PMID: 14532992
    3. RA-RhoGAP transduces a signal from Rap1 to Rho and regulates the neurite outgrowth PMID: 16014623
  • 相关疾病：
    A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL) (PubMed:15543602). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes (PubMed:15543602).
  • 组织特异性：
    Expressed predominantly in the brain. Lower expression is found in lymph nodes.
  • 数据库链接：

    HGNC: 18357

    OMIM: 609568

    KEGG: hsa:57569

    STRING: 9606.ENSP00000260283

    UniGene: Hs.6136

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