Recombinant Human Ras-related protein Rab-15 (RAB15)

^{In Stock}

中文名称：

Recombinant Human Ras-related protein Rab-15 (RAB15)
货号：

CSB-EP019163HU
规格：

￥1536
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

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纯度：

Greater than 95% as determined by SDS-PAGE.
生物活性：

Not Test
基因名：

RAB15
Uniprot No.：

P59190
种属：

Homo sapiens (Human)
蛋白长度：

Full Length
来源：

E.coli
分子量：

25.5 kDa
表达区域：

1-212aa
氨基酸序列

MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELALAELEEEEGKPEGPANSSKTCWC
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

C-terminal 6xHis-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

3-7 business days
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA：

Please contact us to get it.

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功能：

May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.
基因功能参考文献：
1. identified 4 Rab15 isoforms, Rab15CN, Rab15AN1, Rab15AN2 and Rab15AN3 in neuroblastoma cells and demonstrated that Rab15 isoform balance was significantly decreased in spheres of neuroblastoma cells; study suggests Rab15 alternative splicing may serve as a biomarker to discriminate tumor-initiating cells (TICs) from non-TICs in neuroblastoma PMID: 22427180
2. Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells PMID: 21491086
3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
4. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
6. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 19170196
7. Rab15 effector protein is a binding partner for Rab15-GTP. PMID: 16195351
8. Observational study of gene-disease association. (HuGE Navigator) PMID: 19773279
9. Observational study of gene-disease association. (HuGE Navigator) PMID: 19692168
10. Observational study of gene-disease association. (HuGE Navigator) PMID: 19625176
11. Observational study of gene-disease association. (HuGE Navigator) PMID: 18676680
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亚细胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, Rab family
数据库链接：

HGNC: 20150

KEGG: hsa:376267

UniGene: Hs.512492

Recombinant Human Ras-related protein Rab-15 (RAB15)

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