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  4. Recombinant Human Putative helicase Mov10l1 (MOV10L1), partial

Recombinant Human Putative helicase Mov10l1 (MOV10L1), partial

  • 中文名称：
    人MOV10L1重组蛋白
  • 货号：
    CSB-YP871604HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MOV10L1重组蛋白
  • 货号：
    CSB-EP871604HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MOV10L1重组蛋白
  • 货号：
    CSB-EP871604HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MOV10L1重组蛋白
  • 货号：
    CSB-BP871604HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MOV10L1重组蛋白
  • 货号：
    CSB-MP871604HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MOV10L1
  • Uniprot No.：
    Q9BXT6
  • 别名：
    Cardiac helicase activated by MEF2 protein; Cardiac specific RNA helicase; CHAMP; Csm; M10L1_HUMAN; Moloney leukemia virus 10 like protein 1; Moloney leukemia virus 10-like protein 1; MOV10 like 1; MOV10 like protein 1; MOV10-like protein 1; MOV10L1; Mov10l1; Moloney leukemia virus 10 like 1; homolog (mouse); Putative helicase Mov10l1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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MOV10L1 antibodies

靶点详情

  • 功能：
    ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.
  • 基因功能参考文献：
    1. Our results suggest that MOV10L1 gene polymorphisms in the studied infertile males with complete maturation arrest are linked to infertility. PMID: 24817005
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    DNA2/NAM7 helicase family, SDE3 subfamily
  • 组织特异性：
    [Isoform 1]: Specifically expressed in testis.
  • 数据库链接：

    HGNC: 7201

    OMIM: 605794

    KEGG: hsa:54456

    STRING: 9606.ENSP00000262794

    UniGene: Hs.62880

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