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  4. Recombinant Human Protein PRRC2A (PRRC2A), partial

Recombinant Human Protein PRRC2A (PRRC2A), partial

  • 中文名称：
    人PRRC2A重组蛋白
  • 货号：
    CSB-YP342571HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PRRC2A重组蛋白
  • 货号：
    CSB-EP342571HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PRRC2A重组蛋白
  • 货号：
    CSB-EP342571HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PRRC2A重组蛋白
  • 货号：
    CSB-BP342571HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PRRC2A重组蛋白
  • 货号：
    CSB-MP342571HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PRRC2A
  • Uniprot No.：
    P48634
  • 别名：
    HLA-B-associated transcript 2; Large proline-rich protein BAT2; PRC2A_HUMAN; Proline-rich and coiled-coil-containing protein 2A; Protein G2; Protein PRRC2A; Prrc2a
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in the regulation of pre-mRNA splicing.
  • 基因功能参考文献：
    1. The BAT2/BAT3 polymorphisms and specifically the A/C haplotype may represent a novel immunogenetic factor associated with graft rejection in patients undergoing allo-HSCT. PMID: 25111513
    2. Data show the synthetic effect of SNPs on the indices of adiposity and risk of obesity in Chinese girls, but failed to replicate the effect of five separate variants of SEC16B rs10913469, SH2B1 rs4788102, PCSK1 rs6235, KCTD15 rs29941 and BAT2 rs2844479. PMID: 23121087
    3. Single nucleotide polymorphisms at C6orf48, BAT2 and ZBTB12 are associated with estrogen receptor positive breast cancer in the Chinese Han population. PMID: 23079975
    4. Single-nucleotide polymorphism in the BAT2 gene is associated with lung cancer susceptibility. PMID: 23221128
    5. Data indicate that BCL2L11 rs3789068 was associated with an increased risk for B-cell non-Hodgkin lymphoma (NHL), and PRRC2A rs3132453 conferred a reduced risk of B-cell NHL. PMID: 23047821
    6. Results suggest BAT2 -8671, BAT3 8854, and BAT5 22655, 9569 SNPs as well as BAT haplotypes (ATTGTG and ATCATG) might be associated with higher Kawasaki disease susceptibility and coronary artery aneurysm formation. PMID: 20626023
    7. BAT2, MC4R, FTO, Sec16B, SH2B1 genes are associated with genetic susceptibility to obesity in Chinese women. PMID: 20616199
    8. An analysis of 2,162 case-controls demonstrated the first evidence of association between a BAT2 polymorphism (rs1046089) and severe malaria. PMID: 19039607

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  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Limited to cell-lines of leukemic origin.
  • 数据库链接：

    HGNC: 13918

    OMIM: 142580

    KEGG: hsa:7916

    STRING: 9606.ENSP00000365175

    UniGene: Hs.123239

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