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  4. Recombinant Human Nuclear pore complex protein Nup133 (NUP133), partial

Recombinant Human Nuclear pore complex protein Nup133 (NUP133), partial

  • 中文名称：
    人NUP133重组蛋白
  • 货号：
    CSB-YP855476HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NUP133重组蛋白
  • 货号：
    CSB-EP855476HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NUP133重组蛋白
  • 货号：
    CSB-EP855476HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NUP133重组蛋白
  • 货号：
    CSB-BP855476HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NUP133重组蛋白
  • 货号：
    CSB-MP855476HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NUP133
  • Uniprot No.：
    Q8WUM0
  • 别名：
    133 kDa nucleoporin; FLJ10814; hNUP 133; hNUP133; MGC21133; NU133_HUMAN; Nuclear pore complex protein Nup133; Nucleoporin 133kDa; Nucleoporin NUP133; NUP 133; NUP133; OTTHUMP00000061095
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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NUP133 antibodies

靶点详情

  • 功能：
    Involved in poly(A)+ RNA transport. Involved in nephrogenesis.
  • 基因功能参考文献：
    1. human Nup133 contains two domains: a COOH-terminal domain responsible for its interaction with its subcomplex through Nup107; and an NH2-terminal domain whose crystal structure reveals a seven-bladed beta-propeller. PMID: 15557116
    2. When complexed with NUP107, this complex will give the first insights into the protein-protein interactions within a core module of the nuclear pore complex. PMID: 17768364
    3. The significant topological differences between Nup107 and Nup133 suggest that helical nucleoporin domains of the nuclear pore complex scaffold fall in different classes and fulfill largely nonredundant functions. PMID: 18570875
    4. Data present crystal structures of yNup170(979-1502) and hNup107(658-925) x hNup133(517-1156), and conservation of domain arrangement and of tertiary structure suggests that Nup157/170 and Nup133 derived from a common ancestor. PMID: 19674973
  • 亚细胞定位：
    Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore.
  • 蛋白家族：
    Nucleoporin Nup133 family
  • 组织特异性：
    Widely expressed in fetal and adult tissues. Expressed in the brain and kidney.
  • 数据库链接：

    HGNC: 18016

    OMIM: 607613

    KEGG: hsa:55746

    STRING: 9606.ENSP00000261396

    UniGene: Hs.12457

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