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  4. Recombinant Human Neuron navigator 2 (NAV2), partial

Recombinant Human Neuron navigator 2 (NAV2), partial

  • 中文名称：
    人NAV2重组蛋白
  • 货号：
    CSB-YP015479HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NAV2重组蛋白
  • 货号：
    CSB-EP015479HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NAV2重组蛋白
  • 货号：
    CSB-EP015479HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NAV2重组蛋白
  • 货号：
    CSB-BP015479HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NAV2重组蛋白
  • 货号：
    CSB-MP015479HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NAV2
  • Uniprot No.：
    Q8IVL1
  • 别名：
    NAV2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2Neuron navigator 2; EC 3.6.4.12; Helicase APC down-regulated 1; Pore membrane and/or filament-interacting-like protein 2; Retinoic acid inducible in neuroblastoma 1; Steerin-2; Unc-53 homolog 2; unc53H2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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NAV2 antibodies

NAV2 Proteins

靶点详情

  • 功能：
    Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
  • 基因功能参考文献：
    1. NAV2 and CCND2 are novel candidate prognostic markers in uterine leiomyosarcoma and uterine low-grade endometrial stromal sarcoma, respectively. PMID: 28643014
    2. The present study is the first study providing evidence of several genetic variants within the NAV2 gene influencing the risk and age at onset of Alzheimer's disease. PMID: 28778446
    3. interaction between NAV2 and 14-3-3epsilon PMID: 24161943
    4. regulated by all-trans retinoic acid in neuroblastoma cells PMID: 11904404
    5. a novel gene, termed HELAD1 (helicase, APC down-regulated 1) plays important role in colorectal carcinogenesis (HELAD1) PMID: 12214280

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Nav/unc-53 family
  • 组织特异性：
    Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
  • 数据库链接：

    HGNC: 15997

    OMIM: 607026

    KEGG: hsa:89797

    STRING: 9606.ENSP00000379394

    UniGene: Hs.502116

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