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  4. Recombinant Human Myosin-7B (MYH7B), partial

Recombinant Human Myosin-7B (MYH7B), partial

  • 中文名称：
    人MYH7B重组蛋白
  • 货号：
    CSB-YP015301HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MYH7B重组蛋白
  • 货号：
    CSB-EP015301HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MYH7B重组蛋白
  • 货号：
    CSB-EP015301HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MYH7B重组蛋白
  • 货号：
    CSB-BP015301HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MYH7B重组蛋白
  • 货号：
    CSB-MP015301HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MYH7B
  • Uniprot No.：
    A7E2Y1
  • 别名：
    Antigen MLAA-21; cardiac muscle beta isoform; Myh7b; MYH7B_HUMAN; Myosin cardiac muscle beta chain; Myosin heavy chain 7B; Myosin-7B; Slow A MYH14
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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MYH7B antibodies

靶点详情

  • 功能：
    Involved in muscle contraction.
  • 基因功能参考文献：
    1. The actin-based motor myosin-7b (Myo7b) promotes the accumulation of intermicrovillar adhesion complex (IMAC components at microvillar tips. Myo7b is highly enriched at the tips of microvilli in both kidney and intestinal brush borders, and loss of Myo7b in differentiating intestinal epithelial cells disrupts intermicrovillar adhesion and, thus, brush border assembly. PMID: 27666969
    2. Digenic mutational inheritance of the integrin alpha 7 and the myosin heavy chain 7B genes causes congenital myopathy with left ventricular non-compact cardiomyopathy. [MYH7B] PMID: 23800289
    3. Data suggest that transcription and alternative splicing uncouple the level of expression of MYH7b and miR-499 when their coexpression is not required. PMID: 20154144
    4. MYH7b, the ortholog of slow myosin 2 (SM2) of frogs and birds, is detected as mRNA in heart, slow muscles and extraocular muscles. MYH7b protein is detected only in a subset of fibers, corresponding to slow-tonic fibers, in extraocular muscles. PMID: 19948655
  • 亚细胞定位：
    Membrane; Peripheral membrane protein.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 组织特异性：
    Expressed in heart, skeletal muscle, testis, and all specific brain regions examined. Slightly lower expression was detected in ovary and kidney, and intermediate expression was detected in lung, pancreas, spleen and liver.
  • 数据库链接：

    HGNC: 15906

    OMIM: 609928

    KEGG: hsa:57644

    STRING: 9606.ENSP00000262873

    UniGene: Hs.414122

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