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  4. Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17)

Recombinant Human Methyltransferase-like protein 17, mitochondrial (METTL17)

  • 中文名称：
    人METTL17重组蛋白
  • 货号：
    CSB-YP880990HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人METTL17重组蛋白
  • 货号：
    CSB-EP880990HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人METTL17重组蛋白
  • 货号：
    CSB-BP880990HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    METTL17
  • Uniprot No.：
    Q9H7H0
  • 别名：
    METTL17; METT11D1Methyltransferase-like protein 17; mitochondrial; EC 2.1.1.-; False p73 target gene protein; Methyltransferase 11 domain-containing protein 1; Protein RSM22 homolog; mitochondrial
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-456
  • 氨基酸序列
    V APQARALAAL VPGVTQVDNK SGFLQKRPHR QHPGILKLPH VRLPQALANG AQLLLLGSAG PTMENQVQTL TSYLWSRHLP VEPEELQRRA RHLEKKFLEN PDLSQTEEKL RGAVLHALRK TTYHWQELSY TEGLSLVYMA ARLDGGFAAV SRAFHEIRAR NPAFQPQTLM DFGSGTGSVT WAAHSIWGQS LREYMCVDRS AAMLVLAEKL LKGGSESGEP YIPGVFFRQF LPVSPKVQFD VVVSAFSLSE LPSKADRTEV VQTLWRKTGH FLVLVENGTK AGHSLLMDAR DLVLKGKEKS PLDPRPGFVF APCPHELPCP QLTNLACSFS QAYHPIPFSW NKKPKEEKFS MVILARGSPE EAHRWPRITQ PVLKRPRHVH CHLCCPDGHM QHAVLTARRH GRDLYRCARV SSWGDLLPVL TPSAFPPSTA QDPSES
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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METTL17 Proteins

靶点详情

  • 功能：
    Probable S-adenosyl-L-methionine-dependent RNA methyltransferase required to stabilize the mitochondrial small ribosomal subunit (mt-SSU). Required for protein translation in mitochondria.
  • 基因功能参考文献：
    1. METTL17 is a novel coactivator of estrogen receptors and may play a role in breast tumorigenesis. PMID: 26488768
    2. METT11D1 mutations could not explain phenotype of patients with combined oxidative phosphorylation system deficiencies. PMID: 24137763
    3. Possible component of the small subunit of the mitochondrial ribosome, has similarity to yeast Rsm22 (Ykl155c) mitochondrial ribosomal protein. PMID: 11278769
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Methyltransferase superfamily, Rsm22 family
  • 数据库链接：

    HGNC: 19280

    OMIM: 616091

    KEGG: hsa:64745

    STRING: 9606.ENSP00000372445

    UniGene: Hs.512693

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