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  4. Recombinant Human Kinesin-like protein KIF21B (KIF21B), partial

Recombinant Human Kinesin-like protein KIF21B (KIF21B), partial

  • 中文名称：
    人KIF21B重组蛋白
  • 货号：
    CSB-YP012324HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人KIF21B重组蛋白
  • 货号：
    CSB-EP012324HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人KIF21B重组蛋白
  • 货号：
    CSB-EP012324HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人KIF21B重组蛋白
  • 货号：
    CSB-BP012324HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人KIF21B重组蛋白
  • 货号：
    CSB-MP012324HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    KIF21B
  • Uniprot No.：
    O75037
  • 别名：
    KI21B_HUMAN; KIAA0449; KIF21B; Kinesin-like protein KIF21B
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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KIF21B antibodies

靶点详情

  • 功能：
    Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.
  • 基因功能参考文献：
    1. Thus, KIF21B combines microtubule-binding and regulatory activities that together constitute an autonomous microtubule pausing factor. PMID: 28290984
    2. KIF21B is associated with ankylosing spondylitis in a Chinese population of Shandong Province PMID: 25149646
    3. KIF21B may play an important role in the pathogenesis of AS in the Chinese population and might be a new therapeutic target for AS. PMID: 24065353
    4. Data show the association of SNPs in KIF21B with multiple sclerosis in a Belgian study population. PMID: 20587413
    5. Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B as susceptibility loci PMID: 20007504

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 数据库链接：

    HGNC: 29442

    OMIM: 608322

    KEGG: hsa:23046

    STRING: 9606.ENSP00000328494

    UniGene: Hs.169182

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