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  4. Recombinant Human Kinesin-like protein KIF16B (KIF16B), partial

Recombinant Human Kinesin-like protein KIF16B (KIF16B), partial

  • 中文名称：
    人KIF16B重组蛋白
  • 货号：
    CSB-YP846656HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人KIF16B重组蛋白
  • 货号：
    CSB-EP846656HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人KIF16B重组蛋白
  • 货号：
    CSB-EP846656HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人KIF16B重组蛋白
  • 货号：
    CSB-BP846656HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人KIF16B重组蛋白
  • 货号：
    CSB-MP846656HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    KIF16B
  • Uniprot No.：
    Q96L93
  • 别名：
    KIF16B; C20orf23; KIAA1590; SNX23Kinesin-like protein KIF16B; Sorting nexin-23
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.
  • 基因功能参考文献：
    1. The kinesin KIF16B mediates apical transcytosis of transferrin receptor in AP-1B-deficient epithelia. PMID: 23749212
    2. The tubule formations were dependent on microtubule interactions, and specifically controlled by Kif16b and dynein 1. PMID: 22357949
    3. genome-wide significance in genes involved in synaptic signaling (KIF16B; p = 1.27E-08) and neurodevelopment (PAX5; p = 3.58E-08). PMID: 22449649
    4. KIF16B, a kinesin-3, transports early endosomes to the plus end of microtubules in a process regulated by the small GTPase Rab5 and its effector. PMID: 15882625
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Early endosome membrane. Cytoplasm. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 组织特异性：
    Primarily expressed in brain. Also present in kidney, liver, intestine, placenta, leukocytes, heart and skeletal muscle (at protein level).
  • 数据库链接：

    HGNC: 15869

    KEGG: hsa:55614

    STRING: 9606.ENSP00000384164

    UniGene: Hs.101774

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