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  4. Recombinant Human Golgin subfamily B member 1 (GOLGB1), partial

Recombinant Human Golgin subfamily B member 1 (GOLGB1), partial

  • 中文名称：
    人GOLGB1重组蛋白
  • 货号：
    CSB-YP622788HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人GOLGB1重组蛋白
  • 货号：
    CSB-EP622788HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人GOLGB1重组蛋白
  • 货号：
    CSB-EP622788HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人GOLGB1重组蛋白
  • 货号：
    CSB-BP622788HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人GOLGB1重组蛋白
  • 货号：
    CSB-MP622788HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    GOLGB1
  • Uniprot No.：
    Q14789
  • 别名：
    372 kDa Golgi complex associated protein; 372 kDa Golgi complex-associated protein; GCP; GCP372; Giantin; GOGB1_HUMAN; GOLGB1; Golgi autoantigen golgin subfamily a member 1; Golgi autoantigen golgin subfamily b macrogolgin (with transmembrane signal) 1 ; Golgi autoantigen, golgin subfamily b, macrogolgin 1; Golgi complex associated protein 372kDa; Golgi complex-associated protein 372kDa; Golgin B1; Golgin B1, golgi integral membrane protein; Golgin subfamily B member 1; GOLIM1; Macrogolgin; MGC33154
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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GOLGB1 antibodies

靶点详情

  • 功能：
    May participate in forming intercisternal cross-bridges of the Golgi complex.
  • 基因功能参考文献：
    1. Single nucleotide polymorphisms (SNPs) rs1035798 in RAGE gene, rs2073617 and rs2073618 in TNFRSF11B, and rs3732410 in Golgb1 will be investigated on whether there is an association with hemorrhagic stroke (HS) in Chinese population. PMID: 26664786
    2. Partial depletion of giantin or of WDR34 leads to an increase in cilia length consistent with the concept that giantin acts through dynein-2. PMID: 24046448
    3. the spatial organization of the Golgi ribbon is mediated by giantin, which also plays a role in cargo transport and sugar modifications PMID: 23555793
    4. unbiased whole-genome search for genetic modifiers of stroke risk in sickle cell anemia was performed; mutation in GOLGB1 (Y1212C) and mutation in ENPP1 (K173Q) were confirmed as having significant associations with a decreased risk for stroke PMID: 23422753
    5. Data report the characterization of a mammalian coiled-coil protein, CASP, a Golgi protein that shares with giantin a conserved histidine in its transmembrane domain. PMID: 12429822
    6. Giantin binds to Rab6A and Rab1 proteins. PMID: 17475246

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  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type I membrane protein.
  • 数据库链接：

    HGNC: 4429

    OMIM: 602500

    KEGG: hsa:2804

    STRING: 9606.ENSP00000341848

    UniGene: Hs.213389

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