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  4. Recombinant Human Dual serine/threonine and tyrosine protein kinase (DSTYK), partial

Recombinant Human Dual serine/threonine and tyrosine protein kinase (DSTYK), partial

  • 中文名称：
    人DSTYK重组蛋白
  • 货号：
    CSB-YP007213HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人DSTYK重组蛋白
  • 货号：
    CSB-EP007213HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人DSTYK重组蛋白
  • 货号：
    CSB-EP007213HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人DSTYK重组蛋白
  • 货号：
    CSB-BP007213HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人DSTYK重组蛋白
  • 货号：
    CSB-MP007213HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DSTYK
  • Uniprot No.：
    Q6XUX3
  • 别名：
    DSTYK; Dual serine/threonine and tyrosine protein kinase; Dusty PK; Dusty protein kinase; DUSTY_HUMAN; HDCMD38P; KIAA0472; Receptor interacting protein 5; Receptor interacting protein kinase 5; Receptor interacting serine/threonine protein kinase 5; Receptor-interacting serine/threonine-protein kinase 5; RIP homologous kinase; RIP-homologous kinase; RIP5; RIPK5; SgK496; Sugen kinase 496
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

相关产品

DSTYK antibodies

靶点详情

  • 功能：
    Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
  • 基因功能参考文献：
    1. RIPK3 promotes adenovirus type 5 oncolytic activity. PMID: 29238045
    2. we identified a complex homozygous 4-kb deletion/20-bp insertion in DSTYK in all four affected family members with Autosomal-Recessive Complicated Spastic Paraparesis, SPG23 PMID: 28157540
    3. We detected independent DSTYK mutations in 2.3% of patients with congenital abnormalities of the kidney or urinary tract, a finding that suggests that DSTYK is a major determinant of human urinary tract development, downstream of FGF signaling. PMID: 23862974
    4. Confocal imaging of transiently expressed human Dusty-GFP fusion proteins showed a cytoplasmic distribution. PMID: 17123648
  • 相关疾病：
    Congenital anomalies of the kidney and urinary tract 1 (CAKUT1); Spastic paraplegia 23 (SPG23)
  • 亚细胞定位：
    Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Cell junction.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 组织特异性：
    Predominantly expressed in skeletal muscle and testis. Expressed in basolateral and apical membranes of all tubular epithelia. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional
  • 数据库链接：

    HGNC: 29043

    OMIM: 270750

    KEGG: hsa:25778

    STRING: 9606.ENSP00000356130

    UniGene: Hs.6874

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