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  4. Recombinant Human Disks large-associated protein 3 (DLGAP3), partial

Recombinant Human Disks large-associated protein 3 (DLGAP3), partial

  • 中文名称：
    人DLGAP3重组蛋白
  • 货号：
    CSB-YP006942HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人DLGAP3重组蛋白
  • 货号：
    CSB-EP006942HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人DLGAP3重组蛋白
  • 货号：
    CSB-EP006942HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人DLGAP3重组蛋白
  • 货号：
    CSB-BP006942HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人DLGAP3重组蛋白
  • 货号：
    CSB-MP006942HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DLGAP3
  • Uniprot No.：
    O95886
  • 别名：
    DLGAP3; DAP3Disks large-associated protein 3; DAP-3; PSD-95/SAP90-binding protein 3; SAP90/PSD-95-associated protein 3; SAPAP3
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

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DLGAP3 antibodies

靶点详情

  • 功能：
    May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
  • 基因功能参考文献：
    1. several rare variants of the DLGAP3 gene were found in this study which may be associated with schizophrenia. PMID: 23414653
    2. This study provides suggestive evidence that DLGAP3 and its interactive effect with SLC1A1 might be involved in susceptibility to developing OC symptoms in schizophrenia patients receiving AAP treatment. PMID: 21990008
    3. This study generated preliminary evidence to link SAPAP3 variants to the development of earlier onset obsessive-compulsive disorder. PMID: 21295225
    4. DLGAP3 remains a promising candidate gene for Tourette Syndrome. PMID: 21184590
    5. Sapap3 is a promising functional candidate gene for human grooming disorder (obsessive compulsive disorder). PMID: 19051237
    6. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. PMID: 19096451

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  • 亚细胞定位：
    Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
  • 蛋白家族：
    SAPAP family
  • 数据库链接：

    HGNC: 30368

    OMIM: 611413

    KEGG: hsa:58512

    STRING: 9606.ENSP00000235180

    UniGene: Hs.733945

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