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  4. Recombinant Human DDB1- and CUL4-associated factor 13 (DCAF13)

Recombinant Human DDB1- and CUL4-associated factor 13 (DCAF13)

  • 中文名称：
    Recombinant Human DDB1- and CUL4-associated factor 13(DCAF13)
  • 货号：
    CSB-YP882111HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human DDB1- and CUL4-associated factor 13(DCAF13)
  • 货号：
    CSB-EP882111HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human DDB1- and CUL4-associated factor 13(DCAF13)
  • 货号：
    CSB-EP882111HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human DDB1- and CUL4-associated factor 13(DCAF13)
  • 货号：
    CSB-BP882111HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human DDB1- and CUL4-associated factor 13(DCAF13)
  • 货号：
    CSB-MP882111HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DCAF13
  • Uniprot No.：
    Q9NV06
  • 别名：
    DCA13_HUMAN; DCAF13; DDB1 and CUL4 associated factor 13; DDB1- and CUL4-associated factor 13; DKFZP564O0463; GM83; HSPC064; MGC126859; MGC138247; WD repeat and SOF domain-containing protein 1; WD repeats and SOF1 domain containing; WDSOF1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-445
  • 氨基酸序列
    MKVKMLSRNP DNYVRETKLD LQRVPRNYDP ALHPFEVPRE YIRALNATKL ERVFAKPFLA SLDGHRDGVN CLAKHPEKLA TVLSGACDGE VRIWNLTQRN CIRTIQAHEG FVRGICTRFC GTSFFTVGDD KTVKQWKMDG PGYGDEEEPL HTILGKTVYT GIDHHWKEAV FATCGQQVDI WDEQRTNPIC SMTWGFDSIS SVKFNPIETF LLGSCASDRN IVLYDMRQAT PLKKVILDMR TNTICWNPME AFIFTAANED YNLYTFDMRA LDTPVMVHMD HVSAVLDVDY SPTGKEFVSA SFDKSIRIFP VDKSRSREVY HTKRMQHVIC VKWTSDSKYI MCGSDEMNIR LWKANASEKL GVLTSREKAA KDYNQKLKEK FQHYPHIKRI ARHRHLPKSI YSQIQEQRIM KEARRRKEVN RIKHSKPGSV PLVSEKKKHV VAVVK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • 基因功能参考文献：
    1. our findings revealed that the overexpression of DCAF13 in hepatocellular carcinoma was significantly associated with poor survival and may participate in the regulation of cell cycle progression PMID: 28631558
    2. This study suggests that non-synonymous WDSOF1 polymorphisms play a role in the genetic susceptibility to osteoporosis. PMID: 20601284
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    WD repeat DCAF13/WDSOF1 family
  • 数据库链接：

    HGNC: 24535

    OMIM: 616196

    KEGG: hsa:25879

    STRING: 9606.ENSP00000297579

    UniGene: Hs.532265

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