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  4. Recombinant Human Ankyrin repeat and SAM domain-containing protein 1A (ANKS1A), partial

Recombinant Human Ankyrin repeat and SAM domain-containing protein 1A (ANKS1A), partial

  • 中文名称：
    Recombinant Human Ankyrin repeat and SAM domain-containing protein 1A(ANKS1A) ,partial
  • 货号：
    CSB-YP849774HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Ankyrin repeat and SAM domain-containing protein 1A(ANKS1A) ,partial
  • 货号：
    CSB-EP849774HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Ankyrin repeat and SAM domain-containing protein 1A(ANKS1A) ,partial
  • 货号：
    CSB-EP849774HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Ankyrin repeat and SAM domain-containing protein 1A(ANKS1A) ,partial
  • 货号：
    CSB-BP849774HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Ankyrin repeat and SAM domain-containing protein 1A(ANKS1A) ,partial
  • 货号：
    CSB-MP849774HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ANKS1A
  • Uniprot No.：
    Q92625
  • 别名：
    ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1; Ankyrin repeat and SAM domain containing protein 1A; Ankyrin repeat and SAM domain-containing protein 1A; Ankyrin repeat and sterile alpha motif domain containing 1A; ANS1A_HUMAN; KIAA0229; MGC42354; Odin
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction.
  • 基因功能参考文献：
    1. This study reveals a novel mechanism that regulates the loading of RTKs into COPII vesicles. PMID: 27619642
    2. peptide fragments of Odin-Sam1 interacting with EphA2-Sam PMID: 26120079
    3. Odin (ANKS1A) modulates EGF receptor recycling and stability. PMID: 23825523
    4. structural and binding affinity between odin and arap3 PMID: 23239578
    5. RINL, as a GEF for Rab5 subfamily, is implicated in the EphA8-degradation pathway via its interaction with odin. PMID: 22291991
    6. Sam (sterile alpha motif) domains of Odin, a member of the ANKS (ankyrin repeat and sterile alpha motif domain-containing) family of proteins, are important for the regulation of EphA2 endocytosis. PMID: 22332920

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  • 亚细胞定位：
    Cytoplasm. Cell projection. Note=Cytoplasmic before and after growth factor treatment.
  • 组织特异性：
    Widely expressed (at protein level).
  • 数据库链接：

    HGNC: 20961

    OMIM: 608994

    KEGG: hsa:23294

    STRING: 9606.ENSP00000353518

    UniGene: Hs.656492

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