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  4. Recombinant Human Alanine--glyoxylate aminotransferase 2-like 1 (AGXT2L1)

Recombinant Human Alanine--glyoxylate aminotransferase 2-like 1 (AGXT2L1)

  • 中文名称：
    人ETNPPL重组蛋白
  • 货号：
    CSB-YP819453HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人ETNPPL重组蛋白
  • 货号：
    CSB-EP819453HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人ETNPPL重组蛋白
  • 货号：
    CSB-EP819453HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人ETNPPL重组蛋白
  • 货号：
    CSB-BP819453HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人ETNPPL重组蛋白
  • 货号：
    CSB-MP819453HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ETNPPL
  • Uniprot No.：
    Q8TBG4
  • 别名：
    ETNPPL; AGXT2L1Ethanolamine-phosphate phospho-lyase; EC 4.2.3.2; Alanine--glyoxylate aminotransferase 2-like 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-499
  • 氨基酸序列
    MCELYSKRDT LGLRKKHIGP SCKVFFASDP IKIVRAQRQY MFDENGEQYL DCINNVAHVG HCHPGVVKAA LKQMELLNTN SRFLHDNIVE YAKRLSATLP EKLSVCYFTN SGSEANDLAL RLARQFRGHQ DVITLDHAYH GHLSSLIEIS PYKFQKGKDV KKEFVHVAPT PDTYRGKYRE DHADSASAYA DEVKKIIEDA HNSGRKIAAF IAESMQSCGG QIIPPAGYFQ KVAEYVHGAG GVFIADEVQV GFGRVGKHFW SFQMYGEDFV PDIVTMGKPM GNGHPVACVV TTKEIAEAFS SSGMEYFNTY GGNPVSCAVG LAVLDIIENE DLQGNAKRVG NYLTELLKKQ KAKHTLIGDI RGIGLFIGID LVKDHLKRTP ATAEAQHIIY KMKEKRVLLS ADGPHRNVLK IKPPMCFTEE DAKFMVDQLD RILTVLEEAM GTKTESVTSE NTPCKTKMLK EAHIELLRDS TTDSKENPSR KRNGMCTDTH SLLSKRLKT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.
  • 基因功能参考文献：
    1. AGXT2L1 is down-regulated in hepatocellular carcinoma and its low expression indicates a poor prognosis. AGXT2L1 is a crucial gene in the abnormal lipogenesis of HCC tissue. PMID: 26294768
    2. The pH dependence of the catalytic parameters and the pattern of inhibition by the product phosphate and by other anionic compounds suggest that the active site of PEA phospho-lyase is optimized to bind dianionic groups. PMID: 25327712
    3. AGXT2L1 function appears to be rigidly confined to phospholipid metabolism, which is altered in neuropsychiatric disturbances. PMID: 23761375
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Class-III pyridoxal-phosphate-dependent aminotransferase family
  • 数据库链接：

    HGNC: 14404

    OMIM: 614682

    KEGG: hsa:64850

    STRING: 9606.ENSP00000296486

    UniGene: Hs.106576

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