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  4. Recombinant Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial (ACSM2B)

Recombinant Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial (ACSM2B)

  • 中文名称：
    Recombinant Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial(ACSM2B)
  • 货号：
    CSB-YP727854HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial(ACSM2B)
  • 货号：
    CSB-EP727854HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial(ACSM2B)
  • 货号：
    CSB-EP727854HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial(ACSM2B)
  • 货号：
    CSB-BP727854HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Acyl-coenzyme A synthetase ACSM2B, mitochondrial(ACSM2B)
  • 货号：
    CSB-MP727854HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ACSM2B
  • Uniprot No.：
    Q68CK6
  • 别名：
    ACSM2B; ACSM2; HYST1046Acyl-coenzyme A synthetase ACSM2B; mitochondrial; EC 6.2.1.2; Acyl-CoA synthetase medium-chain family member 2B; Benzoate--CoA ligase; EC 6.2.1.25; Butyrate--CoA ligase 2B; Butyryl-coenzyme A synthetase 2B; Middle-chain acyl-CoA synthetase 2B; Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    47-577
  • 氨基酸序列
    ASDV LDHWADMEKA GKRLPSPALW WVNGKGKELM WNFRELSENS QQAANILSGA CGLQRGDRVA VMLPRVPEWW LVILGCIRAG LIFMPGTIQM KSTDILYRLQ MSKAKAIVAG DEVIQEVDTV ASECPSLRIK LLVSEKSCDG WLNFKKLLNE ASTTHHCVET GSQEASAIYF TSGTSGLPKM AEHSYSSLGL KAKMDAGWTG LQASDIMWTI SDTGWILNIL GSLLESWTLG ACTFVHLLPK FDPLVILKTL SSYPIKSMMG APIVYRMLLQ QDLSSYKFPH LQNCLAGGES LLPETLENWR AQTGLDIREF YGQTETGLTC MVSKTMKIKP GYMGTAASCY DVQVIDDKGN VLPPGTEGDI GIRVKPIRPI GIFSGYVENP DKTAANIRGD FWLLGDRGIK DEDGYFQFMG RADDIINSSG YRIGPSEVEN ALMKHPAVVE TAVISSPDPV RGEVVKAFVI LASQFLSHDP EQLTKELQQH VKSVTAPYKY PRKIEFVLNL PKTVTGKIQR TKLRDKEWKM SGKARAQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate.
  • 基因功能参考文献：
    1. This study assessed the naturally observed sequence diversity and protein expression variation of ACSM2A and ACSM2B. The allelic variation, haplotype diversity, Tajima's D values, and phylogenetic analyses indicated that ACSM2A and ACSM2B are highly conserved.The protein expression analyses showed that ACSM2A is the predominant transcript in liver. PMID: 29948332
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20679960
    3. results suggest an involvement of the medium-chain acyl-CoA synthetase 2 (MACS2) Leu513Ser polymorphism in the development of the metabolic syndrome in Caucasian population PMID: 16521160
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 16521160
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    ATP-dependent AMP-binding enzyme family
  • 组织特异性：
    Detected in liver.
  • 数据库链接：

    HGNC: 30931

    OMIM: 614359

    KEGG: hsa:348158

    STRING: 9606.ENSP00000327453

    UniGene: Hs.298252

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