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  4. Recombinant Drosophila melanogaster Vesicle-fusing ATPase 2 (Nsf2), partial

Recombinant Drosophila melanogaster Vesicle-fusing ATPase 2 (Nsf2), partial

  • 中文名称：
    黑腹果蝇Nsf2重组蛋白
  • 货号：
    CSB-YP346160DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Nsf2重组蛋白
  • 货号：
    CSB-EP346160DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Nsf2重组蛋白
  • 货号：
    CSB-EP346160DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Nsf2重组蛋白
  • 货号：
    CSB-BP346160DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Nsf2重组蛋白
  • 货号：
    CSB-MP346160DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Nsf2
  • Uniprot No.：
    P54351
  • 别名：
    Nsf2; CG33101; Vesicle-fusing ATPase 2; EC 3.6.4.6; N-ethylmaleimide-sensitive fusion protein 2; NEM-sensitive fusion protein 2; Vesicular-fusion protein NSF2; dNsf-2; NSF-2
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
  • 基因功能参考文献：
    1. CCM3 and GCKIII prevent tube dilation in Drosophila trachea; tube dilation is suppressed by reduction of NSF2 PMID: 23763949
    2. genetic analysis of suppressors of NSF2 neuromuscular junction overgrowth PMID: 15834148
    3. NSF2(E/Q) larval synapses indicate the NMJ overgrowth phenotype is present at the embryonic neuromuscular synapse. At the ultrastructural level, considerable alterations in the number and distribution of synapses and active zones were found. PMID: 15912502
    4. These data are consistent with a model in which actin filaments promote vesicle mobility and suggest that N-ethylmaleimide sensitive factor participates in establishing or maintaining this population of actin. PMID: 16914524
    5. Interaction of cytoskeleton genes with NSF2-induced neuromuscular junction overgrowth suggests that NSF may function near the top of the actin regulatory pathway. PMID: 17139674

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    AAA ATPase family
  • 组织特异性：
    Nervous system and secretory tissues.
  • 数据库链接：

    KEGG: dme:Dmel_CG33101

    STRING: 7227.FBpp0082346

    UniGene: Dm.6688

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