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  4. Recombinant Drosophila melanogaster Transcription factor kayak, isoforms A/B/F (kay), partial

Recombinant Drosophila melanogaster Transcription factor kayak, isoforms A/B/F (kay), partial

  • 中文名称：
    黑腹果蝇kay重组蛋白
  • 货号：
    CSB-YP325100DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇kay重组蛋白
  • 货号：
    CSB-EP325100DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇kay重组蛋白
  • 货号：
    CSB-EP325100DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇kay重组蛋白
  • 货号：
    CSB-BP325100DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇kay重组蛋白
  • 货号：
    CSB-MP325100DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    kay
  • Uniprot No.：
    P21525
  • 别名：
    kay; Fra; CG15509; Transcription factor kayak; isoforms A/B/F; AP-1; Fos-related antigen; Dfos; dFra
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra.
  • 基因功能参考文献：
    1. In wild-type ovarian cells, c-Fos is post-transcriptionally repressed by Piwi, which destabilized the c-Fos mRNA by promoting the processing of its 3' untranslated region (UTR) into Piwi-interacting RNAs (piRNAs). PMID: 27622269
    2. AP-1-dependent gene transcription is upregulated by increased neural activity during development. PMID: 23293292
    3. Clathrin and AP-1 colocalize at the trans-Golgi network; clathrin and AP-1 colocalize with secretory cargo at the TGN and on immature granules; loss of clathrin or AP-1 leads to a profound block in secretory granule formation. PMID: 21490149
    4. Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation. PMID: 17183370
    5. expression of Fos bZip elicits male-specific phenotypes. PMID: 18924113

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    BZIP family, Fos subfamily
  • 组织特异性：
    Early expression in the embryo is mesodermal and some of this expression is localized to a region surrounding the cephalic furrow. Later in embryonic development expression is ectodermal, corresponding to muscle attachment sites. Also observed in part of
  • 数据库链接：

    KEGG: dme:Dmel_CG33956

    STRING: 7227.FBpp0288515

    UniGene: Dm.6968

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