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  4. Recombinant Drosophila melanogaster Synapsin (Syn), partial

Recombinant Drosophila melanogaster Synapsin (Syn), partial

  • 中文名称：
    黑腹果蝇Syn重组蛋白
  • 货号：
    CSB-YP630514DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Syn重组蛋白
  • 货号：
    CSB-EP630514DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Syn重组蛋白
  • 货号：
    CSB-EP630514DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Syn重组蛋白
  • 货号：
    CSB-BP630514DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Syn重组蛋白
  • 货号：
    CSB-MP630514DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Syn
  • Uniprot No.：
    Q24546
  • 别名：
    Syn; Syn-1; Syn-2; CG3985; Synapsin [Cleaved into: Synapsin-1; Syn1; Syn1-S); Synapsin-2; Syn2)]
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a significant role in nervous system function, which is subtle at the cellular level but manifests itself in complex behavior.
  • 基因功能参考文献：
    1. We show that after odor-high salt conditioning larvae form two parallel memory phases; a short lasting component that depends on cyclic adenosine 3'5'-monophosphate (cAMP) signaling and synapsin gene function PMID: 27768692
    2. Synapsin is required for short- but not longer-term memory. PMID: 26670182
    3. This study report Synapsin as a determinant for memory strength in a behavioral assay of timing-dependent associative plasticity. PMID: 25972175
    4. This study demonistrated that support a model whereby synapsin accumulates at sites of synaptic growth and facilitates budding of new boutons via a cAMP/PKA-dependent pathway. PMID: 25100589
    5. these data support a model in which CaMKII-mediated synapsin phosphorylation in local circuit interneurons induces synaptic vesicle mobilization and thereby presynaptic facilitation of GABA release that underlies olfactory short-term habituation. PMID: 24133261
    6. This study synapsin acts in associative memory trace formation in the mushroom bodies, as a downstream element of AC-cAMP-PKA signaling. PMID: 21518740
    7. these results elucidate a novel synapsin function, specifically, promoting vesicle reuptake and reserve pool formation upon intense stimulation. PMID: 20638447
    8. larval Drosophila can be used as a case study for a role of Synapsin in associative learning PMID: 15930500
    9. synapsin maintains the reserve pool of vesicles and segregation between the recycling and reserve pools PMID: 17904536

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  • 亚细胞定位：
    Cell junction, synapse.
  • 蛋白家族：
    Synapsin family
  • 组织特异性：
    Widely expressed in the embryonic and adult nervous system synaptic terminals.
  • 数据库链接：

    KEGG: dme:Dmel_CG3985

    STRING: 7227.FBpp0099901

    UniGene: Dm.6815

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