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  4. Recombinant Drosophila melanogaster Protein yellow (y), partial

Recombinant Drosophila melanogaster Protein yellow (y), partial

  • 中文名称：
    黑腹果蝇y重组蛋白
  • 货号：
    CSB-YP362843DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇y重组蛋白
  • 货号：
    CSB-EP362843DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇y重组蛋白
  • 货号：
    CSB-EP362843DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇y重组蛋白
  • 货号：
    CSB-BP362843DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇y重组蛋白
  • 货号：
    CSB-MP362843DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    y
  • Uniprot No.：
    P09957
  • 别名：
    y; CG3757; Protein yellow
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Controls the pigmentation pattern of the adult cuticle and larval mouth parts.
  • 基因功能参考文献：
    1. First, the authors show that y is required for the production of black Dopamine-melanin. Then, using in situ hybridization, they show that the expression of y is strongly modulated by temperature in the abdominal epidermis of pharate females but not in bristles. PMID: 28230190
    2. the negative effect of transcription of the Drosophila genes white and yellow remained, but weakened with increased distance between the leading promoter and enhancer and with decreased distance between the enhancer and target promoter PMID: 27183791
    3. role of yellow gene sequences from -70 to-146 bp in the transcriptional activation at the end of terminally truncated chromosome in Drosophila melanogaster PMID: 26163206
    4. Study shows that the polyadenylation signal from the yellow gene cannot efficiently terminate transcription when located in the gene intron and that the Su(Hw)-dependent 1A2 insulator cannot enhance the polyadenylation signal efficiency PMID: 24993965
    5. Data show that flies lacking yar RNAs are viable and show no overt morphological defects, consistent with maintained transcriptional regulation of the adjacent yellow (y) and achaete (ac) genes. PMID: 21775470
    6. Both insulators support basal activity of the yellow and white promoters in eyes. PMID: 21862564
    7. Data indicate that homolog pairing at yellow is efficient, as complementation was disrupted only in the presence of chromosomal rearrangements that break PMID: 19667134
    8. yellow transvection can occur at multiple genomic locations and indicate that the Drosophila genome generally is permissive to enhancer action in trans PMID: 11904429
    9. Drosophila y(yellow) and e(ebony) genes play critical, reciprocal roles in the formation of melanin patterns. PMID: 11934851
    10. Immunohistochemical colocalization of Yellow and male-specific Fruitless in Drosophila melanogaster neuroblasts PMID: 12054512
    11. Evolutionary changes in Yellow expression correlate with divergent melanin patterns and are a result of evolution in both cis- and trans-regulation. PMID: 12372246
    12. the data of this study suggest that y is a downstream member of the fru branch of the D. melanogaster sex determination hierarchy, where it plays a currently unknown role in the development of adult male wing extension during courtship. PMID: 12605459
    13. how the position in the genome affects the extent of repression of the yellow gene by the Su(Hw) insulator PMID: 12856417
    14. proposed that Yellow acts as a growth factor- or hormone-like molecule in the development of pigmentation and sexual behavior; discussed the consistency of this theory with experimental observations in flies and humans PMID: 14575686
    15. Multiple regulatory elements in the promoter region of the yellow gene. PMID: 15714950
    16. Contains a regulatory sequence that is required for normal male mating success. PMID: 16272418
    17. The effects of genotype of the strains, C(1)DX, ywf/Y, 23.5 MRF/CyL4, and C(1)DX,yf; pi2, on locus-specific instability in the yellow gene of the strains y(2-717, y(2-715), and y(2-700 ) from Uman' population of Drosophila melanogaster was studied. PMID: 17899812
    18. An increased amount of AUBERGINE interferes with the regular functioning of the somatic RNA interference pathway. PMID: 18385112
    19. Yellow locus residing at the very end of X chromosome (region 1A5-8 of cytologic map) carries significantly more transposon than retrotransposon-induced mutations, as compared to white locus (regions 3C2). PMID: 18822793

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Major royal jelly protein family
  • 数据库链接：

    KEGG: dme:Dmel_CG3757

    STRING: 7227.FBpp0070070

    UniGene: Dm.23761

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