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  4. Recombinant Drosophila melanogaster Probable ubiquitin carboxyl-terminal hydrolase FAF (faf), partial

Recombinant Drosophila melanogaster Probable ubiquitin carboxyl-terminal hydrolase FAF (faf), partial

  • 中文名称：
    黑腹果蝇faf重组蛋白
  • 货号：
    CSB-YP347643DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇faf重组蛋白
  • 货号：
    CSB-EP347643DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇faf重组蛋白
  • 货号：
    CSB-EP347643DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇faf重组蛋白
  • 货号：
    CSB-BP347643DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇faf重组蛋白
  • 货号：
    CSB-MP347643DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    faf
  • Uniprot No.：
    P55824
  • 别名：
    faf; CG1945Probable ubiquitin carboxyl-terminal hydrolase FAF; EC 3.4.19.12; Protein fat facets; Ubiquitin thioesterase FAF; Ubiquitin-specific-processing protease FAF; Deubiquitinating enzyme FAF
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Ubiquitin C-terminal hydrolase involved in development and the imd/NF-kappa-B (IMD) signaling cascade. Required for eye and embryo development, and plays a role in compound eye assembly and oogenesis respectively. In the larval eye disks, cells outside the assembling facets require this protein for short-range cell interactions that prevent the mystery cells from becoming photoreceptors. Also required for nuclear migration and cellularization in early embryogenesis and could play a role in pole cell determination, development or function. Regulates the IMD signaling cascade at later stages of infection (around 6 hours post-infection) by inhibiting the expression of the antimicrobial peptides Dpt and Dro. Acts by modulating the state of imd polyubiquitination and/or stability; a function which appears to be independent of its enzymatic activity. In turn, imd enhances the polyubiquitination and stability of faf suggesting that they may form a regulatory feedback mechanism within the Imd pathway.
  • 基因功能参考文献：
    1. Faf inhibits the IMD pathway by modulating the state of Imd ubiquitination and/or stability. PMID: 23919485
  • 蛋白家族：
    Peptidase C19 family
  • 组织特异性：
    Eye disks and ovaries. Expressed in larval fat body.
  • 数据库链接：

    KEGG: dme:Dmel_CG1945

    STRING: 7227.FBpp0085202

    UniGene: Dm.3133

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