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  4. Recombinant Drosophila melanogaster Optomotor-blind protein (bi), partial

Recombinant Drosophila melanogaster Optomotor-blind protein (bi), partial

  • 中文名称：
    Recombinant Drosophila melanogaster Optomotor-blind protein(bi) ,partial
  • 货号：
    CSB-YP630511DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Optomotor-blind protein(bi) ,partial
  • 货号：
    CSB-EP630511DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Optomotor-blind protein(bi) ,partial
  • 货号：
    CSB-EP630511DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Optomotor-blind protein(bi) ,partial
  • 货号：
    CSB-BP630511DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Optomotor-blind protein(bi) ,partial
  • 货号：
    CSB-MP630511DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    bi
  • Uniprot No.：
    Q24432
  • 别名：
    bi; OMB; CG3578; Optomotor-blind protein; Lethal(1)optomotor-blind; L(1)omb; Protein bifid
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential protein that may function as a transcription regulator. Vital for pupal development. Required for proper development of the optic lobes and wings, and abdominal pigmentation.
  • 基因功能参考文献：
    1. complementary expression of omb and Iro-C establishes the wing hinge/notum fold formation PMID: 27212024
    2. Optomotor-blind does not prevent apoptosis in the haltere but rather limits growth by repressing several Decapentaplegic and Hedgehog targets. PMID: 25793870
    3. results suggest that the primary effect of Omb is the blocking of Jak/STAT signaling by repressing transcription of upd which encodes the Jak receptor ligand Unpaired. PMID: 25781970
    4. Since loss of omb disrupts horizontal system and vertical system cell development, we assume that HS/VS ontogeny is controlled by Omb target genes. PMID: 24912380
    5. Dpp, via omb, promoted proliferation in the lateral and repressed proliferation in the medial wing disc. Omb controlled the regional proliferation rate by oppositely regulating transcription of the microRNA gene bantam in medial versus lateral wing disc. PMID: 23821035
    6. four new omb mutations were isolated and characterized. PMID: 20033428
    7. dysfunction of omb elicits hyperactivation of Hh signaling that causes an ectopic folding and local overgrowth in the wing columnar epithelium PMID: 17573067
    8. OMB exprsssion in glial cells is required for correct axonal projection across the Drosophila inner optic chiasma. PMID: 18234176

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  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    In third-instar larvae, expressed in the brain region that will develop into optic lobes and more weakly in the thoracic part of the ventral ganglion.
  • 数据库链接：

    KEGG: dme:Dmel_CG3578

    STRING: 7227.FBpp0303589

    UniGene: Dm.1683

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