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  4. Recombinant Drosophila melanogaster Irregular chiasm C-roughest protein (rst), partial

Recombinant Drosophila melanogaster Irregular chiasm C-roughest protein (rst), partial

  • 中文名称：
    黑腹果蝇rst重组蛋白
  • 货号：
    CSB-YP600070DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇rst重组蛋白
  • 货号：
    CSB-EP600070DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇rst重组蛋白
  • 货号：
    CSB-EP600070DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇rst重组蛋白
  • 货号：
    CSB-BP600070DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇rst重组蛋白
  • 货号：
    CSB-MP600070DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    rst
  • Uniprot No.：
    Q08180
  • 别名：
    rst; CG4125; Irregular chiasm C-roughest protein; Protein IRREC
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for correct axonal pathway formation in the optic lobe and for programmed cell death in the developing retina.
  • 基因功能参考文献：
    1. The data reveal a novel requirement for Sac1 in promoting microtubule stability and suggest that Rst trafficking occurs in a microtubule- and exocyst-dependent manner. PMID: 29752385
    2. the roles of Rst, Hbs, Kirre and SNS in the spacing of bristles of the anterior wing margin, are explored. PMID: 26053791
    3. Cindr recapitulates both proposed functions of its mammalian orthologs Cd2ap and Cin85: targeting the IgCAMs Rst and Hbs for endocytosis and stabilizing these heterophilic IgCAM complexes. PMID: 23027549
    4. Analysis of a cytoplasmic motif present in Kirre and IrreC/Rst revealed a functionally required, conserved 12 AA motif (KIN1 motif). PMID: 22792268
    5. Findings suggest a general mechanism by which rst and kirre expression could be fine tuned to optimize their redundant roles during development. PMID: 21857931
    6. identified two cell-adhesion molecules: Hibris, which is expressed in post-mitotic lamina precursor cells; and Roughest, which is expressed on retinal axons. PMID: 20724453
    7. A novel relationship is described between the Crumbs partner beta(Heavy)-spectrin (beta(H)), the zona adherens and Roughest. PMID: 20048344
    8. rst gene has a role in the differentiation of secondary/tertiary pigment cell fate PMID: 12782271
    9. Roughest (Rst) is a cell adhesion molecule of the immunoglobulin superfamily with pleiotropic functions during the development of Drosophila melanogaster. PMID: 15278452
    10. The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila PMID: 16380111
    11. describe the expression pattern and of Rst in wild type and rst(D) mutants, showing that downregulation in salivary glands at the beginning of pupal stage is an important factor in implementation of the autophagic program of this tissue in space and time PMID: 19415632

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  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Postembryonic expression is strong in the developing optic lobe and in the eye imaginal disk.
  • 数据库链接：

    KEGG: dme:Dmel_CG4125

    STRING: 7227.FBpp0070537

    UniGene: Dm.1692

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