Recombinant Drosophila melanogaster Integrin alpha-PS3 (scb), partial
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中文名称:黑腹果蝇scb重组蛋白
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货号:CSB-YP526130DLU
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规格:
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来源:Yeast
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其他:
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中文名称:黑腹果蝇scb重组蛋白
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货号:CSB-EP526130DLU
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规格:
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来源:E.coli
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其他:
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中文名称:黑腹果蝇scb重组蛋白
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货号:CSB-EP526130DLU-B
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规格:
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来源:E.coli
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共轭:Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他:
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中文名称:黑腹果蝇scb重组蛋白
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货号:CSB-BP526130DLU
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规格:
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来源:Baculovirus
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其他:
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中文名称:黑腹果蝇scb重组蛋白
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货号:CSB-MP526130DLU
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规格:
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来源:Mammalian cell
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其他:
产品详情
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纯度:>85% (SDS-PAGE)
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基因名:scb
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Uniprot No.:
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别名:scb; alphaPS3; Vol; CG8095; Integrin alpha-PS3; Position-specific antigen subunit alpha-3; Protein scab; Protein volado) [Cleaved into: Integrin alpha-PS3 heavy chain; Integrin alpha-PS3 light chain]
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种属:Drosophila melanogaster (Fruit fly)
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蛋白长度:Partial
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蛋白标签:Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
产品提供形式:Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
复溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事项:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet :Please contact us to get it.
靶点详情
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功能:Integrin alpha-PS3/beta-PS is a receptor for laminin. Also binds to wb. Important during embryogenesis for the development of the trachea, dorsal vessel and salivary gland, as well as for dorsal closure. Required for short-term memory processes. Minor involvement in the establishment of the oocyte anterior-posterior length. Plays a role in timely border cell migration during oogenesis, probably mediated by JNK signaling. Integrin alpha-PS3/Itgbn is required for effective phagocytosis of apoptotic cells during embryonic development and for the phagocytic elimination of S.aureus by mediating the binding of S.aureus peptidoglycan to larval hemocytes, which probably activates a signaling pathway involving Rac1 and Rac2. Integrin alpha-PS3/Itgbn also regulates Fak activity during neuromuscular junction (NMJ) growth and is required for its activation in presynapsis of NMJs. Seems to be dispensable for major morphogenetic processes.
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基因功能参考文献:
- We identify a role for the alphaPS3, betaPS1 Integrin dimer in both the early establishment of the apical, pre-luminal domain, as well as a requirement upon Robo for maintained apicalisation of proteins required for lumen formation. PMID: 22353787
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亚细胞定位:Apical cell membrane; Single-pass type I membrane protein. Lateral cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Apical membrane localization in primordial dorsal-appendage cells at oogenesis stages 10B and 11. Later, weakly expressed in lateral membrane of cells surrounding the outgrowing dorsal appendages.
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蛋白家族:Integrin alpha chain family
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组织特异性:Expressed in embryonic and larval hemocytes (at protein level). Expressed in tissues undergoing invagination, tissue movement and morphogenesis such as salivary gland, trachea, midgut endoderm, dorsal vessel, midline of the ventral nerve cord, amnioserosa
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数据库链接:
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