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  4. Recombinant Drosophila melanogaster Dynein light chain 2, cytoplasmic (Cdlc2)

Recombinant Drosophila melanogaster Dynein light chain 2, cytoplasmic (Cdlc2)

  • 中文名称：
    Recombinant Drosophila melanogaster Dynein light chain 2, cytoplasmic(Cdlc2)
  • 货号：
    CSB-YP528535DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Dynein light chain 2, cytoplasmic(Cdlc2)
  • 货号：
    CSB-EP528535DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Dynein light chain 2, cytoplasmic(Cdlc2)
  • 货号：
    CSB-EP528535DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Dynein light chain 2, cytoplasmic(Cdlc2)
  • 货号：
    CSB-BP528535DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Dynein light chain 2, cytoplasmic(Cdlc2)
  • 货号：
    CSB-MP528535DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cdlc2
  • Uniprot No.：
    O96860
  • 别名：
    Cdlc2; CG5450Dynein light chain 2; cytoplasmic; 8 kDa dynein light chain
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-89
  • 氨基酸序列
    MSDRKAVIKN ADMSEEMQQD AVDCATQALE KYNIEKDIAA FIKKEFDKKY NPTWHCIVGR NFGSYVTHET RHFIYFYLGQ VAILLFKSG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a non-catalytic accessory component of a dynein complex.
  • 基因功能参考文献：
    1. Results show assembled dynein IC as an elongated, flexible polybivalent duplex, and suggest that polybivalency is an important general mechanism for constructing stable yet reversible and functionally versatile complexes. PMID: 19759397
    2. The induced folding of cytoplasmic dynein intermediate chain IC(1-289) upon LC8 light chain binding suggests that LC8 could act through the intermediate chain to facilitate dynein assembly or regulate cargo-binding interactions. PMID: 15581372
    3. We propose that Msn functions together with Bic-D to regulate the apical localization of dynein in generating directed nuclear migration within differentiating R-cell precursor cells. PMID: 15582780
    4. Dynein light chain 1 regulates dynamin-mediated F-actin assembly during sperm individualization in Drosophila PMID: 15829565
    5. dynein-dynactin, abnormal spindle protein (Asp), and KLP10A have roles in Drosophila spindle pole organization PMID: 15888542
    6. Dynein-mediated transport of specific RNAs along specialized networks of microtubules increases the efficiency of their delivery, over the flow of general cytoplasmic components, into the oocyte PMID: 17442699

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Dynein light chain family
  • 数据库链接：

    KEGG: dme:Dmel_CG5450

    STRING: 7227.FBpp0077590

    UniGene: Dm.1988

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