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  4. Recombinant Danio rerio Retinal homeobox protein Rx3 (rx3)

Recombinant Danio rerio Retinal homeobox protein Rx3 (rx3)

  • 中文名称：
    斑马鱼rx3重组蛋白
  • 货号：
    CSB-YP520357DIL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斑马鱼rx3重组蛋白
  • 货号：
    CSB-EP520357DIL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斑马鱼rx3重组蛋白
  • 货号：
    CSB-EP520357DIL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斑马鱼rx3重组蛋白
  • 货号：
    CSB-BP520357DIL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斑马鱼rx3重组蛋白
  • 货号：
    CSB-MP520357DIL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    rx3
  • Uniprot No.：
    O42358
  • 别名：
    rx3; Retinal homeobox protein Rx3
  • 种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-292
  • 氨基酸序列
    MRLVGSQYKD MEDRLSPSAR LVRSPGSQTR IHSIESILGF KGETLFHPAF PYGSGKTGKD TEHLSPKKDS NKHFDGVCRS TVMVSPDLPD ADGGKLSDDE NPKKKHRRNR TTFTTFQLHE LERAFEKSHY PDVYSREELA LKVNLPEVRV QVWFQNRRAK WRRQEKLEVS SIKLQESSML SIPRSGPLSL GSGLPLEPWL TGPISTSSSP LQSLPSFITP QQAVPASYTP PQFLSSSTLN HSLPHIGAVC PPYQCSGFMD KFSLQEADPR NTSIASLRMK AKEHIQSIGK TW
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.
  • 基因功能参考文献：
    1. Shh and Rx3 govern formation of a distinct progenitor domain that elaborates patterning through its anisotropic growth and differentiation. PMID: 27317806
    2. rx3 mutation leads to microphthalmia, incomplete eye maturation, and dramatic increases in apoptotic eye progenitors PMID: 15183718
    3. In addition to controlling optic lobe evagination and proliferation, chk/rx3 also determines cellular fate. PMID: 16300752
    4. The process segregating the telencephalic and eye fields is isolated from diencephalic patterning, and is mediated by Rx3. PMID: 16818451
    5. lmo4b has an essential role in forebrain development as a modulator of six3 and rx3 expression, and thus indirectly influences neural cell fate commitment, cell proliferation and tissue growth in the anterior CNS. PMID: 17692837

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Paired homeobox family, Bicoid subfamily
  • 数据库链接：

    KEGG: dre:30474

    STRING: 7955.ENSDARP00000069319

    UniGene: Dr.540

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