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  4. Recombinant Chicken Progesterone receptor (PGR), partial

Recombinant Chicken Progesterone receptor (PGR), partial

  • 中文名称：
    鸡PGR重组蛋白
  • 货号：
    CSB-YP017875CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡PGR重组蛋白
  • 货号：
    CSB-EP017875CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡PGR重组蛋白
  • 货号：
    CSB-EP017875CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡PGR重组蛋白
  • 货号：
    CSB-BP017875CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡PGR重组蛋白
  • 货号：
    CSB-MP017875CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PGR
  • Uniprot No.：
    P07812
  • 别名：
    PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
  • 基因功能参考文献：
    1. The results indicate that PR percentage and the PR-A and PR-B ratio change according to the cell type of the oviduct magnum and in an age-specific manner. PMID: 27526993
    2. Data suggest that progesterone receptors A (PRA) and B (PRB) and progesterone receptor membrane component 1 (PGRMC1) are expressed in neurons of embryonic dorsal root ganglia. PMID: 23913445
    3. Content of progesterone receptor (PR)isoforms related to degree of brain development in chicks PMID: 14511763
    4. a portion of the cytoplasmic receptor is seen as an oligomeric complex, whereas, in the nucleus, most, if not all receptor molecules are in dissociated form PMID: 14514410
    5. In Estrogen receptor-/PR- breasst tumors in age > 50, ER+/PR+ status was associated with higher frequency of methylation. PMID: 15041725
    6. Collectively, elevated circulating estrogen and/or decreased progesterone levels may have contributed to the upregulation of PGR mRNA and isoforms A and B in the pituitary gland of restricted ovulator hen, which have a point mutation in VLDLR. PMID: 16677794
    7. Results demonstrate that PR isoforms content presents a sexual dimorphism in the brain of chickens that changes in tissue- and age-specific manner, and suggest that these variations contribute to the regulation of progesterone actions in brain. PMID: 17141234
    8. A side-by-side comparison of the Hsp90-dependent chaperoning of Chk1 to that of the progesterone receptor (PR) was performed to show that these distinct types of clients have different chaperoning requirements. PMID: 18229454

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  • 亚细胞定位：
    Nucleus. Cytoplasm.; [Isoform A]: Nucleus. Cytoplasm. Note=Mainly nuclear.
  • 蛋白家族：
    Nuclear hormone receptor family, NR3 subfamily
  • 组织特异性：
    Oviduct and bursa of Fabricius.
  • 数据库链接：

    KEGG: gga:396198

    STRING: 9031.ENSGALP00000027736

    UniGene: Gga.705

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