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  4. Recombinant Chicken Nitric oxide synthase, inducible (NOS2), partial

Recombinant Chicken Nitric oxide synthase, inducible (NOS2), partial

  • 中文名称：
    鸡NOS2重组蛋白
  • 货号：
    CSB-YP856188CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡NOS2重组蛋白
  • 货号：
    CSB-EP856188CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡NOS2重组蛋白
  • 货号：
    CSB-EP856188CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡NOS2重组蛋白
  • 货号：
    CSB-BP856188CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡NOS2重组蛋白
  • 货号：
    CSB-MP856188CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NOS2
  • Uniprot No.：
    Q90703
  • 别名：
    NOS2; Nitric oxide synthase; inducible; EC 1.14.13.39; Inducible NO synthase; Inducible NOS; iNOS; Macrophage NOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. NO may serve as both a paracrine and autocrine signal for modulating osteoclast bone resorption. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
  • 基因功能参考文献：
    1. palmitate causes an increase in cellular eNOS and iNOS with the resultant NO production serving to protect cardiomyocytes from palmitate-induced cell death. PMID: 15050530
    2. CAT-1 isoform plays a role in L-Arg uptake, and L-Arg-mediated elevation of NO via iNOS promotes the growth of chick intestinal epithelial cells. PMID: 25336270
    3. iNOS gene polymorphism analyzed by PCR-RFLP method revealed difference in allele frequency. Kadaknath breed males had higher allele B frequency (0.81) than Aseel breed males (0.56). PMID: 21607608
    4. in the embryonic cardiovascular system, KLF-2 is expressed in regions of highest shear stress, and ET-1 and NOS-3 expression is related to shear stress PMID: 15108309
    5. The increase in nitric oxide synthase expression observed following posthatched retinal removal could be indicative of nitric oxide participation in plasticity processes, triggered by deafferentation. PMID: 15372492
    6. results imply that tryptophan metabolism and its effect on the availability of substrate for PARP1 regulates iNOS transcription and consequently NO production in interferon gamma stimulated macrophages PMID: 18082271
    7. Data concluded that the mutation of iNOS and hypoxic increase of its expression were important base for adaptability to hypoxia in Tibetan chicken. PMID: 19586893

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  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    NOS family
  • 数据库链接：

    KEGG: gga:395807

    STRING: 9031.ENSGALP00000034026

    UniGene: Gga.3327

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