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  4. Recombinant Chicken Neuropilin-1 (NRP1), partial

Recombinant Chicken Neuropilin-1 (NRP1), partial

  • 中文名称：
    鸡NRP1重组蛋白
  • 货号：
    CSB-YP016091CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡NRP1重组蛋白
  • 货号：
    CSB-EP016091CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡NRP1重组蛋白
  • 货号：
    CSB-EP016091CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡NRP1重组蛋白
  • 货号：
    CSB-BP016091CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡NRP1重组蛋白
  • 货号：
    CSB-MP016091CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NRP1
  • Uniprot No.：
    P79795
  • 别名：
    NRP1; NRP; Neuropilin-1; A5 protein
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Regulates mitochondrial iron transport via interaction.
  • 基因功能参考文献：
    1. NRP1-mediated Sema3A signals provide repulsive signals for MAP2-positive neurons to segregate tectal layers, which is important in order to coordinate laminar organization of the optic tectum. PMID: 25183873
    2. This study demonstrates that the environmental toxin, sodium arsenite, induced angiogenesis by altering the expression of miRNAs and their cognate mRNA targets. PMID: 21503876
    3. with the reduction of neuropilin-1 function, neural crest cells still form segmental migratory streams, suggesting that initial neural crest cell migration and invasion of the branchial arches are separable processes PMID: 16959234
    4. post-transcriptional and local control of the availability of the Sema3A receptor neuropilin 1 at the growth cone surface PMID: 18039974
  • 亚细胞定位：
    Mitochondrion membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Neuropilin family
  • 组织特异性：
    Developing nervous system; optic tectum (layers D and E of SGFS), amacrine cells of retina, neurites of dorsal root ganglia. Also expressed in non-neuronal cells, e.g. blood vessels in the entire embryo.
  • 数据库链接：

    KEGG: gga:395560

    STRING: 9031.ENSGALP00000011550

    UniGene: Gga.4032

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