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  4. Recombinant Chicken Interferon-induced GTP-binding protein Mx (MX), partial

Recombinant Chicken Interferon-induced GTP-binding protein Mx (MX), partial

  • 中文名称：
    鸡MX重组蛋白
  • 货号：
    CSB-YP845863CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡MX重组蛋白
  • 货号：
    CSB-EP845863CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡MX重组蛋白
  • 货号：
    CSB-EP845863CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡MX重组蛋白
  • 货号：
    CSB-BP845863CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡MX重组蛋白
  • 货号：
    CSB-MP845863CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MX
  • Uniprot No.：
    Q90597
  • 别名：
    MX; Interferon-induced GTP-binding protein Mx; Interferon-inducible Mx protein
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
  • 基因功能参考文献：
    1. These results demonstrated that a single amino acid polymorphism at 631 aa of the chicken Mx protein altered both the antiviral activity and intracellular localization. PMID: 23201406
    2. The current study provides valuable information on the effect of the Mx1 gene on the genetic resistance to avian influenza virus in chickens, and Mx1 will not be applicable for enhancing genetic resistance to AIV infection in chickens. PMID: 23155008
    3. the antiviral effect of type I IFN in chicken cells was not dependent on Mx, and both isoforms of chicken Mx protein appear to lack GTPase activity PMID: 21632756
    4. Following intranasal infection with HPAIV strain A/Chicken/Queretaro/14588-19/1995 H5N2, chickens homozygous for Asn631 allele were significantly more resistant to disease based on early mortality, morbidity, or virus shedding than Ser631 homozygotes. PMID: 21286706
    5. the natural cytoplasmic localisation of the chicken Mx protein does not account for its lack of antiviral activity PMID: 20808435
    6. The reduction in viral yield did not differ significantly among Mx genotypes, indicating that Mx Asn631 is not a pivotal determinant of resistance to this strain of IBDV in chicken embryo fibroblast cultures. PMID: 20608522
    7. The distribution of various alleles of the Mx gene among wild and domestic chicken populations are reported. PMID: 16830876
    8. The findings demonstrate that Asn631 chicken Mx alleles do not inhibit influenza virus replication of the five strains tested here PMID: 18508886

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
  • 数据库链接：

    KEGG: gga:395313

    STRING: 9031.ENSGALP00000025952

    UniGene: Gga.131

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