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  4. Recombinant Chicken DNA damage-binding protein 1 (DDB1), partial

Recombinant Chicken DNA damage-binding protein 1 (DDB1), partial

  • 中文名称：
    Recombinant Chicken DNA damage-binding protein 1(DDB1) ,partial
  • 货号：
    CSB-YP767283CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Chicken DNA damage-binding protein 1(DDB1) ,partial
  • 货号：
    CSB-EP767283CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Chicken DNA damage-binding protein 1(DDB1) ,partial
  • 货号：
    CSB-EP767283CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Chicken DNA damage-binding protein 1(DDB1) ,partial
  • 货号：
    CSB-BP767283CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Chicken DNA damage-binding protein 1(DDB1) ,partial
  • 货号：
    CSB-MP767283CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DDB1
  • Uniprot No.：
    Q805F9
  • 别名：
    DDB1; RCJMB04_6h2DNA damage-binding protein 1; DDB p127 subunit; Damage-specific DNA-binding protein 1; UV-damaged DNA-binding factor
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (Probable). The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1. May play a role in the regulation of the circadian clock.
  • 基因功能参考文献：
    1. These results demonstrate that the DDB1 gene is indispensable for cell viability in higher vertebrates and this conditional DDB1-knockout clone would be highly useful for the functional analysis of DDB1. PMID: 17976535
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DDB1 family
  • 数据库链接：

    KEGG: gga:374050

    STRING: 9031.ENSGALP00000039807

    UniGene: Gga.12977

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