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  4. Recombinant Chicken Actin filament-associated protein 1 (AFAP1), partial

Recombinant Chicken Actin filament-associated protein 1 (AFAP1), partial

  • 中文名称：
    Recombinant Chicken Actin filament-associated protein 1(AFAP1) ,partial
  • 货号：
    CSB-YP835459CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Chicken Actin filament-associated protein 1(AFAP1) ,partial
  • 货号：
    CSB-EP835459CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Chicken Actin filament-associated protein 1(AFAP1) ,partial
  • 货号：
    CSB-EP835459CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Chicken Actin filament-associated protein 1(AFAP1) ,partial
  • 货号：
    CSB-BP835459CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Chicken Actin filament-associated protein 1(AFAP1) ,partial
  • 货号：
    CSB-MP835459CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    AFAP1
  • Uniprot No.：
    Q90738
  • 别名：
    AFAP1Actin filament-associated protein 1; 110 kDa actin filament-associated protein; AFAP-110; Neural actin filament protein; pp110
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions as an adapter molecule that links other proteins to the actin cytoskeleton. May function in facilitating interactions between SRC and actin filaments. May modulate changes in actin filament integrity and induce lamellipodia formation. Can cross-link actin filaments into both network and bundle structures.
  • 基因功能参考文献：
    1. results indicate that the association of AFAP with F-actin through actin-binding domain is crucial for AFAP to regulate cytoskeletal structures PMID: 21984596
    2. Data indicate that in addition to its role in the regulation of cytoskeletal structures, AFAP may also be involved in c-Src mediated SRE/AP-1 transactivation. PMID: 21236256
    3. The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src PMID: 9350057
    4. AFAP-120, a variant form of the Src SH2/SH3-binding partner AFAP-110, is detected in brain and contains a novel internal sequence which binds to a 67-kDa protein. PMID: 7876134
    5. Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate PMID: 8247004

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton, stress fiber.
  • 组织特异性：
    Isoform 2 is specifically expressed in brain.
  • 数据库链接：

    KEGG: gga:374034

    STRING: 9031.ENSGALP00000025034

    UniGene: Gga.185

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