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  4. Recombinant Bovine Interferon-induced GTP-binding protein Mx1 (MX1), partial

Recombinant Bovine Interferon-induced GTP-binding protein Mx1 (MX1), partial

  • 中文名称：
    牛MX1重组蛋白
  • 货号：
    CSB-YP015249BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛MX1重组蛋白
  • 货号：
    CSB-EP015249BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛MX1重组蛋白
  • 货号：
    CSB-EP015249BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛MX1重组蛋白
  • 货号：
    CSB-BP015249BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛MX1重组蛋白
  • 货号：
    CSB-MP015249BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MX1
  • Uniprot No.：
    P79135
  • 别名：
    MX1; Interferon-induced GTP-binding protein Mx1; Myxoma resistance protein 1; Myxovirus resistance protein 1
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Interferon-induced dynamin-like GTPase with antiviral activity against rabies virus (RABV), vesicular stomatitis virus (VSV) and murine pneumonia virus (MPV). Isoform 1 but not isoform 2 shows antiviral activity against vesicular stomatitis virus (VSV).
  • 基因功能参考文献：
    1. MX1-a, MX1B and MX2 are affected by the type I IFN pathway during pregnancy and are involved in an immune response to protect the mother and fetus PMID: 26498202
    2. The replication levels of foot-and-mouth disease virus RNA were promoted by silencing bovine Mx1. PMID: 26982472
    3. Overexpression of bovine Mx1 protein inhibits the replication of foot-and-mouth disease virus. PMID: 24294956
    4. Data indicate that the expression profiles of ISG15, MX1, MX2, and OAS1 could be a useful diagnostic biomarker of gestation. PMID: 23384108
    5. The proximal GC boxes were found to be essential for IFN response in the bovine Mx1 promoter with the deletion mutants. PMID: 19203250
    6. Mx1 is cytoplasmic. Mx1B is mainly nuclear. An Arg-rich nuclear localization signal was found in 27 AAs specific for Mx1B. N-terminus-deleted Mx1B is only cytoplasmic. The deleted-Mx1B-expressing cells had positive antiviral activity against VSVDeltaG*-G. PMID: 19951175
    7. A new bovine Mx gene (designated Mx1B) was isolated from the endometrial cDNA library of the early pregnant cow. PMID: 14994826

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  • 亚细胞定位：
    Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region.; [Isoform 2]: Nucleus.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
  • 组织特异性：
    Ubiquitously expressed.
  • 数据库链接：

    KEGG: bta:280872

    STRING: 9913.ENSBTAP00000041289

    UniGene: Bt.4675

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