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  4. Recombinant Bovine Cocaine- and amphetamine-regulated transcript protein (CARTPT)

Recombinant Bovine Cocaine- and amphetamine-regulated transcript protein (CARTPT)

  • 中文名称：
    Recombinant Bovine Cocaine- and amphetamine-regulated transcript protein(CARTPT)
  • 货号：
    CSB-YP734674BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Bovine Cocaine- and amphetamine-regulated transcript protein(CARTPT)
  • 货号：
    CSB-EP734674BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Bovine Cocaine- and amphetamine-regulated transcript protein(CARTPT)
  • 货号：
    CSB-EP734674BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Bovine Cocaine- and amphetamine-regulated transcript protein(CARTPT)
  • 货号：
    CSB-BP734674BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Bovine Cocaine- and amphetamine-regulated transcript protein(CARTPT)
  • 货号：
    CSB-MP734674BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CARTPT
  • Uniprot No.：
    Q68RJ9
  • 别名：
    CARTPT; CART; Cocaine- and amphetamine-regulated transcript protein [Cleaved into: CART(1-39); CART(42-89)]
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    28-116
  • 氨基酸序列
    QED AELQPRALDI YSAVEDASHE KELIEALQEV LKKLKSKRIP IYEKKYGQVP MCDAGEQCAV RKGARIGKLC DCPRGTSCNS FLLKCL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus.
  • 基因功能参考文献：
    1. CART peptide in the normal pancreas has been identified in intrapancreatic ganglia, nerve fibres and in endocrine cells of Langerhans islets and exocrine pancreas. PMID: 25953739
    2. these results demonstrate hormonal regulation of granulosa cell CART binding in vitro and temporal regulation of CART binding in subordinate follicles during dominant follicle selection. Results also suggest that CART signaling may help suppress estradiol-producing capacity of the F2 (subordinate) follicle during this time period. PMID: 24174573
    3. cocaine and amphetamine regulated transcript PMID: 23084786
    4. CART may be a novel local regulator of follicular atresia in the bovine ovary[CART] PMID: 15271876
    5. DNA sequence of the complete coding region of the bovine CART gene PMID: 15670137
    6. Potent inhibitory effects of CART on multiple components of the follitropin signaling pathway linked to follicular development. PMID: 17569753
    7. The intracellular mechanism of action of CART in regulation of FSH-induced MAPK signaling. PMID: 18818282
    8. Two single-nucleotide polymorphisms show an association between genotype and body weight. PMID: 19005236
    9. A potential stage-specific regulatory role for CART in negative regulation of estradiol production associated with selection of the dominant follicle. PMID: 19439726

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    CART family
  • 数据库链接：

    KEGG: bta:493726

    STRING: 9913.ENSBTAP00000055162

    UniGene: Bt.20015

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