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  4. Recombinant Bovine Alpha-S1-casein (CSN1S1)

Recombinant Bovine Alpha-S1-casein (CSN1S1)

  • 中文名称：
    Recombinant Bovine Alpha-S1-casein(CSN1S1)
  • 货号：
    CSB-YP006060BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Bovine Alpha-S1-casein(CSN1S1)
  • 货号：
    CSB-EP006060BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Bovine Alpha-S1-casein(CSN1S1)
  • 货号：
    CSB-BP006060BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Bovine Alpha-S1-casein(CSN1S1)
  • 货号：
    CSB-MP006060BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CSN1S1
  • Uniprot No.：
    P02662
  • 别名：
    CSN1S1Alpha-S1-casein; allergen Bos d 8) [Cleaved into: Antioxidant peptide]
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    16-214
  • 氨基酸序列
    RPKHP IKHQGLPQEV LNENLLRFFV APFPEVFGKE KVNELSKDIG SESTEDQAME DIKQMEAESI SSSEEIVPNS VEQKHIQKED VPSERYLGYL EQLLRLKKYK VPQLEIVPNS AEERLHSMKE GIHAQQKEPM IGVNQELAYF YPELFRQFYQ LDAYPSGAWY YVPLGTQYTD APSFSDIPNP IGSENSEKTT MPLW
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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CSN1S1 Proteins

靶点详情

  • 功能：
    Important role in the capacity of milk to transport calcium phosphate.; Antioxidant peptide has 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity.
  • 基因功能参考文献：
    1. There were no associations between x genotype and fertility related traits in this study. PMID: 27065254
    2. The results give insight in phosphorylation of alpha(S1)-CN-8P and alpha(S1)-CN-9P, which seem to be regulated by a different set of genes. PMID: 25200775
    3. Report proteomic detection of bovine alpha-S1-casein in term and preterm human colostrum. PMID: 23755758
    4. Data indicate that the pepsin-pancreatin digest of alphaS-Casein exhibited anxiolytic-like activity. PMID: 23580614
    5. The genetic effects of thyroglobulin and casein alpha s1 alpha in the body fat distribution of cattle are reported. PMID: 23148258
    6. Alpha-S2-casein was less effective at preventing fibril formation by modified kappa-casein, whereas alpha- and alpha-S1 casein were comparably potent inhibitors. PMID: 21457703
    7. Single or multiple amino acid substitutions within IgE-binding epitopes result in reduced binding of milk-specific IgE antibodies. Critical amino acids should be evaluated with individual patient sera to determine B-cell-epitope heterogeneity. PMID: 12897753
    8. determination of T cell reactive epitopes PMID: 15482858
    9. EMSA analysis comparing allelic variants of a polymorphic AP-1 binding site in the promoter region of CSN1S1; specific and reduced protein binding of oligonucleotides containing the G variant of the CSN1S1-175bp binding site was shown PMID: 15905454
    10. An isoelectrofocusing pattern was identified, which may result from a novel CSN1S1 variant, named CSN1S1*I, migrating at an intermediate position between CSN1S1*B and CSN1S1*C. PMID: 18096958
    11. Substitution effects of paternal CSN2alpha (s1) allele versus CSN2 alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not. PMID: 18263971

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Alpha-casein family
  • 组织特异性：
    Mammary gland specific. Secreted in milk.
  • 数据库链接：

    KEGG: bta:282208

    STRING: 9913.ENSBTAP00000010119

    UniGene: Bt.59369

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