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  4. Recombinant Bovine Adrenodoxin, mitochondrial (FDX1)

Recombinant Bovine Adrenodoxin, mitochondrial (FDX1)

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  • 中文名称：
    牛FDX1重组蛋白
  • 货号：
    CSB-EP008570BO
  • 规格：
    ￥2328
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP008570BO could indicate that this peptide derived from E.coli-expressed Bos taurus (Bovine) FDX1.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP008570BO could indicate that this peptide derived from E.coli-expressed Bos taurus (Bovine) FDX1.
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    FDX1
  • Uniprot No.：
    P00257
  • 别名：
    FDX1; ADX; Adrenodoxin; mitochondrial; Adrenal ferredoxin; Ferredoxin-1; Hepato-ferredoxin
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    E.coli
  • 分子量：
    19.5 kDa
  • 表达区域：
    59-186aa
  • 氨基酸序列
    SSSEDKITVHFINRDGETLTTKGKIGDSLLDVVVQNNLDIDGFGACEGTLACSTCHLIFEQHIFEKLEAITDEENDMLDLAYGLTDRSRLGCQICLTKAMDNMTVRVPDAVSDARESIDMGMNSSKIE
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer，50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

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FDX1 Proteins

靶点详情

  • 功能：
    Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage to produce pregnenolone, the precursor of most steroid hormones. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons.
  • 基因功能参考文献：
    1. Data indicate that the autodisplayed adrenodoxin (Adx) showed reversible redox reactions via direct electron transfer to the mercaptoundecanoic acid (MUA)-modified gold electrode. PMID: 25858110
    2. Kinetic and optical biosensor study of adrenodoxin mutant AdxS112W displaying an enhanced interaction towards the cholesterol side chain cleavage enzyme (CYP11A1). PMID: 21526428
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Adrenodoxin/putidaredoxin family
  • 组织特异性：
    Detected in adrenal cortex and corpus luteum (at protein level).
  • 数据库链接：

    KEGG: bta:281157

    STRING: 9913.ENSBTAP00000015660

    UniGene: Bt.1573

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