Recombinant Bacillus anthracis Thymidylate kinase (tmk)

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中文名称：

炭疽杆菌tmk重组蛋白
货号：

CSB-EP007226BQG
规格：

￥2328
图片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

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纯度：

Greater than 90% as determined by SDS-PAGE.
基因名：

tmk
Uniprot No.：

C3LJ02
别名：

tmk; BAMEG_0039Thymidylate kinase; EC 2.7.4.9; dTMP kinase
种属：

Bacillus anthracis (strain CDC 684 / NRRL 3495)
蛋白长度：

Full Length
来源：

E.coli
分子量：

27.8kDa
表达区域：

1-208aa
氨基酸序列

MKGLFVTIEGPEGSGKTTLIQSLLPYFEQKEQKVMATREPGGIAISEDIRTILHKQEYTMMEARTEALLYAAARRQHLVEKVMPALNEDYLVLCDRFIDSSLAYQGYARGLGMDKVFEINRFATEDCMPSLTIYLDIEPEVGLARIAKDAGREVNRLDMEDISFHKRVREGYLQVVERFSDRIVLVNADQPMEKLIEEVIQVIEDKLL
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白标签：

N-terminal 6xHis-tagged
产品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
缓冲液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
储存条件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
货期：

3-7 business days
注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
产品描述：

The full-length cDNA ORF of Bacillus anthracis Thymidylate kinase (tmk) was N-terminally tagged a 6xHis and then expressed in E.coli. The Recombinant Bacillus anthracis tmk obtained was purified using SDS-PAGE analysis and got over 90% of purity. Under reducing conditions, the tmk protein migrated to an approximately 28 kDa molecular mass band on the SDS-PAGE gel. This recombinant tmk protein may be used to produce specific antibodies or find uses in the DNA synthesis-related studies.

Tmk is a key enzyme exerting an important role in DNA synthesis. It catalyzes the conversion of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP), with ATP as the preferred phosphoryl donor and in the presence of Mg2+. It takes place at the junction of the de novo and salvage pathways for thymidine triphosphate (dTTP) synthesis. Tmk is thus regarded as a potential therapeutic target for the development of antibacterial, antiparasitic, and anticancer drugs.
Datasheet & COA：

Please contact us to get it.

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功能：

Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
蛋白家族：

Thymidylate kinase family
数据库链接：

KEGG: bah:BAMEG_0039

Recombinant Bacillus anthracis Thymidylate kinase (tmk)

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