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  4. Recombinant Arabidopsis thaliana Adagio protein 2 (ADO2), partial

Recombinant Arabidopsis thaliana Adagio protein 2 (ADO2), partial

  • 中文名称：
    Recombinant Arabidopsis thaliana Adagio protein 2(ADO2) ,partial
  • 货号：
    CSB-YP823824DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Adagio protein 2(ADO2) ,partial
  • 货号：
    CSB-EP823824DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Adagio protein 2(ADO2) ,partial
  • 货号：
    CSB-EP823824DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Adagio protein 2(ADO2) ,partial
  • 货号：
    CSB-BP823824DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Adagio protein 2(ADO2) ,partial
  • 货号：
    CSB-MP823824DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ADO2
  • Uniprot No.：
    Q8W420
  • 别名：
    ADO2; FKL1; LKP2; At2g18915; F19F24.11; Adagio protein 2; F-box only protein 2c; FBX2c; Flavin-binding kelch repeat F-box protein 1-like protein 1; FKF1-like protein 1; LOV kelch protein 2
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of an E3 ubiquitin ligase complex that plays a central role in blue light-dependent circadian cycles. Acts as a blue light photoreceptor, due to the presence of FMN, that mediates light-regulated protein degradation of critical clock components by targeting them to the proteasome complex. The SCF(ADO2) E3 ubiquitin ligase complex is involved in the regulation of circadian clock-dependent processes including the transition to flowering time, hypocotyl elongation, cotyledons and leaf movement rhythms. APRR1/TOC1 and APRR5 seem to be substrates of the SCF(ADO2) complex. ADO2 interacts with ADO3 and export it to cytoplasmic speckles, preventing the interaction of ADO3 with CDF1. Ubiquitination of ADO2 is not involved in this recruitment.
  • 基因功能参考文献：
    1. Data indicate that although cryptochrome 2 physically interacts with CIB1 in response to blue light, ZEITLUPE and LOV KELCH PROTEIN 2 are required for the function and blue-light suppression of degradation of CIB1. PMID: 24101505
    2. Both LKP2 and ZTL suppress early flowering, especially under short-day (noninductive) conditions, and that such suppression is dependent on FKF1. PMID: 21518052
    3. ZTL, FKF1, and LKP2 together regulate TOC1 and PRR5 degradation and are major contributors to determining the period of circadian oscillation and enhancing robustness. PMID: 20354196
    4. LKP2, a nuclear protein, interacted not only with itself but also with other members of the family, LKP1 and FKF1. PMID: 15310821
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    ADAGIO family
  • 组织特异性：
    Weakly expressed in seedlings, root tips, stems, leaves, flowers, young siliques, sepals and seeds.
  • 数据库链接：

    KEGG: ath:AT2G18915

    STRING: 3702.AT2G18915.2

    UniGene: At.19440

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