SN38 Recombinant Monoclonal Antibody
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中文名称:SN38重组抗体
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货号:CSB-RA187707I1m
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规格:¥3000
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图片:
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The Binding Activity of Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) with Anti-SN38 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) at 2 μg/mL can bind Anti-SN38 antibody, the EC50 is 3.326 to 4.721 ng/mL.
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其他:
产品详情
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产品描述:SN38 Recombinant Monoclonal Antibody(Code: CSB-RA187707I1m)是一种高特异性抗体,靶向SN38分子(7-ethyl-10-hydroxycamptothecin),该分子是拓扑异构酶I抑制剂伊立替康的活性代谢产物,在肿瘤研究领域被广泛用于诱导DNA损伤及细胞凋亡机制研究。本抗体通过重组技术制备,经ELISA方法严格验证,在1:5000至1:50000的宽泛稀释范围内表现出优异的检测灵敏度和线性关系,可精准识别天然构象的SN38分子。其高批次稳定性与低交叉反应性设计,适用于定量分析SN38在细胞模型或体外药理学研究中的分布与作用,例如评估药物递送效率、代谢动力学或肿瘤细胞耐药性机制等实验场景。推荐应用于ELISA平台检测,支持细胞培养上清、裂解液等样本类型的分析,为抗肿瘤药物开发及分子毒理学研究提供可靠工具。该产品仅供科研使用,不涉及任何临床相关用途。
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基因名:SN38
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别名:SN38, 7-Ethyl-10-hydroxycamptothecin
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反应种属:Human
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免疫原:SN38-BSA
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标记方式:Non-conjugated
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克隆类型:Monoclonal
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抗体亚型:IgG2a
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纯化方式:Affinity-chromatography
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克隆号:10G11D5
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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推荐稀释比:
Application Recommended Dilution ELISA 1:5000-1:50000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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