Your Good Partner in Biology Research

SN38 Recombinant Monoclonal Antibody

  • 中文名称:
    SN38重组抗体
  • 货号:
    CSB-RA187707I1m
  • 规格:
    ¥3000
  • 图片:
    • The Binding Activity of Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) with Anti-SN38 antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) at 2 μg/mL can bind Anti-SN38 antibody, the EC50 is 3.326 to 4.721 ng/mL.
  • 其他:

产品详情

  • 产品描述:
    SN38 Recombinant Monoclonal Antibody(Code: CSB-RA187707I1m)是一种高特异性抗体,靶向SN38分子(7-ethyl-10-hydroxycamptothecin),该分子是拓扑异构酶I抑制剂伊立替康的活性代谢产物,在肿瘤研究领域被广泛用于诱导DNA损伤及细胞凋亡机制研究。本抗体通过重组技术制备,经ELISA方法严格验证,在1:5000至1:50000的宽泛稀释范围内表现出优异的检测灵敏度和线性关系,可精准识别天然构象的SN38分子。其高批次稳定性与低交叉反应性设计,适用于定量分析SN38在细胞模型或体外药理学研究中的分布与作用,例如评估药物递送效率、代谢动力学或肿瘤细胞耐药性机制等实验场景。推荐应用于ELISA平台检测,支持细胞培养上清、裂解液等样本类型的分析,为抗肿瘤药物开发及分子毒理学研究提供可靠工具。该产品仅供科研使用,不涉及任何临床相关用途。
  • 基因名:
    SN38
  • 别名:
    SN38, 7-Ethyl-10-hydroxycamptothecin
  • 反应种属:
    Human
  • 免疫原:
    SN38-BSA
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Monoclonal
  • 抗体亚型:
    IgG2a
  • 纯化方式:
    Affinity-chromatography
  • 克隆号:
    10G11D5
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA
  • 推荐稀释比:
    Application Recommended Dilution
    ELISA 1:5000-1:50000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价